7-azido-4-methylcoumarin
7-Azido-4-Methylcoumarin
CAS: 95633-27-5
Molecular Formula: C10H7N3O2
7-azido-4-methylcoumarin - Names and Identifiers
| Name | 7-Azido-4-Methylcoumarin |
| Synonyms | Hymecromone Impurity 4 7-Azido-4-Methylcoumarin 7-azido-4-methylcoumarin 7-azido-4-methylchromen-2-one |
| CAS | 95633-27-5 |
7-azido-4-methylcoumarin - Physico-chemical Properties
| Molecular Formula | C10H7N3O2 |
| Molar Mass | 201.18148 |
| Melting Point | 117.8°C |
| Appearance | powder |
| Storage Condition | Room Temprature |
7-azido-4-methylcoumarin - Introduction
7-Azido-4-Methylcoumarin (7-azido-4-methylcoumarin) is a synthetic organic compound with the chemical formula C10H6N4O2. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 7-Azido-4-Methylcoumarin is a white crystalline powder.
-Solubility: It has good solubility in most organic solvents such as chloroform and dimethyl sulfoxide.
-Melting point: Its melting point range is 176-177°C.
-Optical properties: It absorbs light in the ultraviolet-visible spectral region, and its maximum absorption wavelength is 346 nm.
Use:
-Photosensitive dye: 7-Azido-4-Methylcoumarin is a photosensitive dye that can be used as a fluorescent probe to detect the structure and function of proteins, nucleic acids and other molecules in biochemical experiments.
-Ignition agent: Due to the presence of azide groups, this compound can be used as an ignition agent to produce explosion or combustion reactions in some specific applications.
Preparation Method:
- 7-Azido-4-Methylcoumarin can be obtained by reacting 4-methyl coumarin with iodoyl chloride (ICl) to obtain 4-azido-3-methylcoumarin, which is then reduced to obtain 7-Azido-4-Methylcoumarin under the catalysis of N-methyl-N-aza-butanedione (MNAD).
Safety Information:
- 7-Azido-4-Methylcoumarin is an explosive compound and should be handled with care.
-Avoid contact with skin and eyes, use protective gloves and eye protection if necessary.
-Avoid contact with combustibles and oxidants during operation.
Nature:
-Appearance: 7-Azido-4-Methylcoumarin is a white crystalline powder.
-Solubility: It has good solubility in most organic solvents such as chloroform and dimethyl sulfoxide.
-Melting point: Its melting point range is 176-177°C.
-Optical properties: It absorbs light in the ultraviolet-visible spectral region, and its maximum absorption wavelength is 346 nm.
Use:
-Photosensitive dye: 7-Azido-4-Methylcoumarin is a photosensitive dye that can be used as a fluorescent probe to detect the structure and function of proteins, nucleic acids and other molecules in biochemical experiments.
-Ignition agent: Due to the presence of azide groups, this compound can be used as an ignition agent to produce explosion or combustion reactions in some specific applications.
Preparation Method:
- 7-Azido-4-Methylcoumarin can be obtained by reacting 4-methyl coumarin with iodoyl chloride (ICl) to obtain 4-azido-3-methylcoumarin, which is then reduced to obtain 7-Azido-4-Methylcoumarin under the catalysis of N-methyl-N-aza-butanedione (MNAD).
Safety Information:
- 7-Azido-4-Methylcoumarin is an explosive compound and should be handled with care.
-Avoid contact with skin and eyes, use protective gloves and eye protection if necessary.
-Avoid contact with combustibles and oxidants during operation.
Last Update：2024-04-10 22:29:15
