7-diethylamino-3-thenoylcoumarin

7-diethylamino-3-thenoylcoumarin - Names and Identifiers

Name	7-(diethylamino)-3-(thiophen-2-ylcarbonyl)-2H-chromen-2-one
Synonyms	7-diethylamino-3-thenoylcoumarin 7-DIETHYLAMINO-3-THENOYLCOUMARIN 7-(Diethylamino)-3-(thiophene-3-carbonyl)-2H-chromen-2-one 7-(Diethylamino)-3-(thiophene-2-carbonyl)-2H-chromen-2-one 7-(diethylamino)-3-(thiophen-2-ylcarbonyl)-2H-chromen-2-one 2H-1-Benzopyran-2-one, 7-(diethylamino)-3-(2-thienylcarbonyl)-
CAS	77820-11-2
EINECS	145-632-3
InChI	InChI=1/C18H17NO3S/c1-3-19(4-2)13-8-7-12-10-14(18(21)22-15(12)11-13)17(20)16-6-5-9-23-16/h5-11H,3-4H2,1-2H3

7-diethylamino-3-thenoylcoumarin - Physico-chemical Properties

Molecular Formula	C18H17NO3S
Molar Mass	327.4
Density	1.2165 (rough estimate)
Melting Point	138-142 °C
Boling Point	533.3±50.0 °C(Predicted)
Flash Point	276.3°C
Vapor Presure	1.88E-11mmHg at 25°C
pKa	2.74±0.20(Predicted)
Storage Condition	Room Temprature
Refractive Index	1.7000 (estimate)

7-diethylamino-3-thenoylcoumarin - Risk and Safety

Safety Description	24/25 - Avoid contact with skin and eyes.
HS Code	29349990

7-diethylamino-3-thenoylcoumarin - Introduction

7-(diethylamino)-3-(thiophen-2-ylcarbonyl)-2H-chromen-2-one is an organic compound with the chemical formula C19H19NO3S. Its nature is as follows:

1. Appearance: white crystalline solid
2. Melting point: about 165-170°C
3. Solubility: Soluble in some polar solvents, such as dimethyl sulfoxide and dichloromethane

7-(diethylamino)-3-(thiophen-2-ylcarbonyl)-2H-chromen-2-one is mainly used in the field of medical research, with antibacterial, anti-inflammatory and anti-tumor activities. Because of its molecular structure contains thiophene and coumarin groups, it has the characteristics of potential drug lead compounds in medical and pharmaceutical chemistry research.

preparation method, 7-(diethylamino)-3-(thiophen-2-ylcarbonyl)-2H-chromen-2-one can be synthesized by thiophene formylation reaction. The specific method is as follows: first, 2-thiophenecarboxylic acid and diethylamine are reacted under appropriate conditions to generate the corresponding amide. Then, through the acyl chloride reaction of the amide, and then condensation with 2H-coumarin, the target product is finally obtained.

Regarding safety information, 7-(diethylamino)-3-(thiophen-2-ylcarbonyl)-2H-chromen-2-one is a chemical reagent and has certain toxicity. During use or operation, strictly follow the relevant safety procedures, wear appropriate personal protective equipment, and avoid direct contact with skin and inhalation of dust. At the same time, care should be taken to keep it properly away from fire sources and oxidants to prevent fire or explosion. If you accidentally touch or eat, please get help from a professional doctor in time.

Last Update：2024-04-09 21:48:26