7-羟基吲哚-2-羧酸乙酯 - Names and Identifiers
7-羟基吲哚-2-羧酸乙酯 - Physico-chemical Properties
| Molecular Formula | C11H11NO3
|
| Molar Mass | 205.21 |
| Density | 1.326±0.06 g/cm3(Predicted) |
| Melting Point | 200-202 °C(Solv: methanol (67-56-1)) |
| Boling Point | 410.4±25.0 °C(Predicted) |
| pKa | 9.66±0.40(Predicted) |
7-羟基吲哚-2-羧酸乙酯 - Introduction
1H-Indole-2-carboxylic acid, 7-hydroxy-, ethyl ester is an organic compound with the chemical formula C11H11NO3. It is a compound structurally similar to an indole derivative in which the carboxyl and hydroxyl groups are located at the 2 and 7 positions, respectively.
The compound is widely used in the field of chemical synthesis and medicine. In chemical synthesis, it can be used as an intermediate for the synthesis of compounds with pharmacological activity. In the field of medicine, it has antiviral, antibacterial, anticancer and other biological activities.
The method for preparing 1H-Indole-2-carboxylic acid, 7-hydroxy-, ethyl ester is generally obtained by reacting 7-hydroxyindole-2-carboxylic acid with ethanol. The specific steps can be divided into three steps: first, the reaction of 7-hydroxyindole-2-carboxylic acid with a protective agent (such as methyl hydrogen silicone oil) to obtain the corresponding protected ester, the resulting compound is reacted with an alcohol, such as ethanol, to form the final product.
Regarding safety information, 1H-Indole-2-carboxylic acid, 7-hydroxy-, ethyl ester generally has no obvious health and environmental hazards under regular experimental conditions. However, in handling and use, it is still necessary to follow safe practices, such as wearing appropriate protective equipment (such as gloves and glasses), ensuring good ventilation, and avoiding inhalation, ingestion or skin contact. If accidentally splashed into the eyes or skin, rinse immediately with plenty of water and seek medical help. In addition, the compound should be stored in a dry, cool, well-ventilated place, away from ignition and flammable materials.
Last Update：2024-04-09 21:01:54