70533-96-9
Boc-L-leucine amide
CAS: 70533-96-9
Molecular Formula: C11H22N2O3
70533-96-9 - Names and Identifiers
| Name | Boc-L-leucine amide |
| Synonyms | Boc-L-Leu-NH2 BOC-L-LEU-NH2 Boc-L-leucine amide N-α-(t-Butoxycarbonyl)-L-leucinamide N-tert-Butoxycarbonyl-L-leucine amide N-tert-Butoxycarbonyl-L-leucine amide N~2~-(tert-butoxycarbonyl)-L-leucinamide tert-butyl N-[(1S)-1-carbamoyl-3-methylbutyl]carbamate (S)-tert-Butyl (1-aMino-4-Methyl-1-oxopentan-2-yl)carbaMate Carbamic acid, N-[(1S)-1-(aminocarbonyl)-3-methylbutyl]-, 1,1-dimethylethyl ester |
| CAS | 70533-96-9 |
| InChI | InChI=1/C11H22N2O3/c1-7(2)6-8(9(12)14)13-10(15)16-11(3,4)5/h7-8H,6H2,1-5H3,(H2,12,14)(H,13,15)/t8-/m0/s1 |
70533-96-9 - Physico-chemical Properties
| Molecular Formula | C11H22N2O3 |
| Molar Mass | 230.3 |
| Density | 1.028±0.06 g/cm3(Predicted) |
| Melting Point | 150-151 °C |
| Boling Point | 375.0±25.0 °C(Predicted) |
| Flash Point | 180.6°C |
| Vapor Presure | 8E-06mmHg at 25°C |
| pKa | 11.38±0.46(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.464 |
70533-96-9 - Introduction
Boc-L-leucine (Boc-L-leucine) is an organic compound commonly used in chemical synthesis and pharmaceutical research.
Nature:
Boc-L-leucine amide is white crystal or crystalline powder. Its chemical formula is C11H22N2O3 and its molecular weight is 230.30g/mol. It is a derivative of leucine in which Boc represents a protecting group tert-butyloxycarbonyl.
Use:
Boc-L-leucine is widely used in peptide synthesis, especially in pharmaceutical research for the synthesis of polypeptide compounds. It can be used as a synthetic drug metabolic intermediate, peptide biomimetic immobilization carrier and for the synthesis of biologically active short peptides.
Preparation Method:
The preparation method of Boc-L-leucine amide usually involves the activation of L-leucine and the introduction of the corresponding protecting group. A typical method of preparation is to react L-leucine with tert-butyloxycarbonyl chloride to give Boc-L-leucine. The Boc-L-leucine is then converted to the Boc-L-leucine by an amidation reaction.
Safety Information:
Boc-L-leucine the safety information of amide has not been fully studied, according to known information, it may be irritating to skin, eyes and respiratory tract. Wear suitable personal protective equipment when handling the compound to avoid inhalation, contact with skin and eyes. At the same time, in the preparation and use of the process should follow the correct laboratory safety procedures. For more detailed safety information, please refer to the Safety Data Sheet (MSDS) of the relevant chemical.
Nature:
Boc-L-leucine amide is white crystal or crystalline powder. Its chemical formula is C11H22N2O3 and its molecular weight is 230.30g/mol. It is a derivative of leucine in which Boc represents a protecting group tert-butyloxycarbonyl.
Use:
Boc-L-leucine is widely used in peptide synthesis, especially in pharmaceutical research for the synthesis of polypeptide compounds. It can be used as a synthetic drug metabolic intermediate, peptide biomimetic immobilization carrier and for the synthesis of biologically active short peptides.
Preparation Method:
The preparation method of Boc-L-leucine amide usually involves the activation of L-leucine and the introduction of the corresponding protecting group. A typical method of preparation is to react L-leucine with tert-butyloxycarbonyl chloride to give Boc-L-leucine. The Boc-L-leucine is then converted to the Boc-L-leucine by an amidation reaction.
Safety Information:
Boc-L-leucine the safety information of amide has not been fully studied, according to known information, it may be irritating to skin, eyes and respiratory tract. Wear suitable personal protective equipment when handling the compound to avoid inhalation, contact with skin and eyes. At the same time, in the preparation and use of the process should follow the correct laboratory safety procedures. For more detailed safety information, please refer to the Safety Data Sheet (MSDS) of the relevant chemical.
Last Update：2024-04-09 21:11:58
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CAS: 70533-96-9
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CAS: 70533-96-9
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