705946-27-6
TYROSINE KINASE-IN-1
CAS: 705946-27-6
Molecular Formula: C26H28FN5O
705946-27-6 - Names and Identifiers
705946-27-6 - Physico-chemical Properties
| Molecular Formula | C26H28FN5O |
| Molar Mass | 445.53 |
| Density | 1.280±0.06 g/cm3(Predicted) |
| Solubility | DMSO : 62.5 mg/mL (140.28 mM) |
| pKa | 11.67±0.20(Predicted) |
| Storage Condition | -20°C |
| In vitro study | Tyrosine kinase-IN-1 is from reference (compound 8K). |
| In vivo study | Tyrosine kinase-IN-1 shows a reasonable PK profile (AUC( 0–∞ )=1.9, t 1/2 =4.6 h). It has a favorable oral bioavailability (F=63%) in rats. |
705946-27-6 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.245 ml | 11.223 ml | 22.445 ml |
| 5 mM | 0.449 ml | 2.245 ml | 4.489 ml |
| 10 mM | 0.224 ml | 1.122 ml | 2.245 ml |
| 5 mM | 0.045 ml | 0.224 ml | 0.449 ml |
Last Update：2024-01-02 23:10:35
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Product Name: TYROSINE KINASE-IN-1 Visit Supplier Webpage Request for quotationCAS: 705946-27-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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