70799-12-1

70799-12-1 - Names and Identifiers

Name	{4-[(Dimethylamino)methyl]phenyl}boronic acid
Synonyms	AKOS BRN-0614 4-[(Dimethylamino)Methyl]Phenylboronic Acid 4-[(DIMETHYLAMINO)METHYL]PHENYLBORONIC ACID {4-[(Dimethylamino)methyl]phenyl}boronic acid B-[4-[(Dimethylamino)methyl]phenyl]boronic acid boronic acid, B-[4-[(dimethylamino)methyl]phenyl]- Boronic acid, B-[4-[(dimethylamino)methyl]phenyl]- 4-((Dimethylamino)methyl)phenylboronic acid hydrochloride Boronic acid, B-[4-[(diMethylaMino)Methyl]phenyl]- hydrochloride
CAS	70799-12-1
InChI	InChI=1/C9H14BNO2/c1-11(2)7-8-3-5-9(6-4-8)10(12)13/h3-6,12-13H,7H2,1-2H3

70799-12-1 - Physico-chemical Properties

Molecular Formula	C9H14BNO2
Molar Mass	179.02
Density	1.09
Boling Point	297℃
Flash Point	134℃
Vapor Presure	0.001mmHg at 25°C
pKa	8.37±0.17(Predicted)
Storage Condition	Inert atmosphere,Store in freezer, under -20°C
Refractive Index	1.54

70799-12-1 - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	R37/38 - Irritating to respiratory system and skin. R41 - Risk of serious damage to eyes
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39 - Wear eye / face protection.

70799-12-1 - Introduction

{4-[(Dimethylamino)methyl]phenyl}boronic acid is an organic boron compound with the chemical formula C9H13BNO2. It is a white crystalline solid, soluble in most organic solvents. The following are some important properties, uses, preparation and safety information about the compound:

Nature:
-Appearance: White crystalline solid
-Molecular weight: 183.02g/mol
-melting point: 121-124 ℃
-Solubility: Soluble in acetone, dimethylformamide and chloroform, slightly soluble in water

Use:
{4-[(Dimethylamino)methyl]phenyl}boronic acid is a commonly used organic synthesis reagent with the following main uses:
-Used to build a carbon-boron bond: Because it has a nucleophilic dimethylamine group and a boronic acid group that can easily react, it is usually used to introduce a phenylboronic acid group to participate in the carbon-boron bond construction reaction.
-Catalyst for chemical reactions: It can be used as a catalyst to participate in cross-coupling reactions (such as Suzuki reaction, Sonogashira reaction, etc.), and is one of the important catalysts for the preparation of organic compounds.
-Used to prepare other organic compounds:{4-[(Dimethylamino)methyl]phenyl}boronic acid can be used as an important intermediate in the fields of drug synthesis, pesticide synthesis, photosensitive material synthesis and liquid crystal molecule synthesis.

Preparation Method:
Generally, the preparation method of {4-[(Dimethylamino)methyl]phenyl}boronic acid includes the following steps:
1. 4-Methylphenylboronic acid is reacted with dimethylamine in an organic solvent to obtain 4-[(dimethylamino) methyl] phenylborate.
2. This salt is then treated with a strong acid to give {4-[(Dimethylamino)methyl]phenyl}boronic acid.

Safety Information:
To date, the potential toxicity and harmfulness of this compound in humans is limited. Appropriate safety precautions should be taken during use and handling, including wearing protective gloves, glasses and laboratory coats. Avoid direct contact with the skin, inhaling its gases, or entering the digestive tract. When used in laboratories or chemical processes, the corresponding operating guidelines and safety regulations should be followed. If necessary, work in a well-ventilated area.

Last Update：2024-04-09 21:04:16