71701-92-3

71701-92-3 - Names and Identifiers

Name	3-Bromo-2-chloro-5-(trifluoromethyl)pyridine
Synonyms	3-Brom-2-chlor-5-(trifluormethyl)pyridin 3-Bromo-2-chloro-5-(trifluoromethyl)pyridine pyridine, 3-bromo-2-chloro-5-(trifluoromethyl)- Pyridine, 3-bromo-2-chloro-5-(trifluoromethyl)- 5-Bromo-6-chloro-alpha,alpha,alpha-trifluoro-3-picoline
CAS	71701-92-3
InChI	InChI=1/C6H2BrClF3N/c7-4-1-3(6(9,10)11)2-12-5(4)8/h1-2H

71701-92-3 - Physico-chemical Properties

Molecular Formula	C6H2BrClF3N
Molar Mass	260.44
Density	1.804±0.06 g/cm3(Predicted)
Melting Point	28-32℃
Boling Point	210.5±35.0 °C(Predicted)
Flash Point	98°(208°F)
Vapor Presure	0.278mmHg at 25°C
Appearance	Solid
Color	Pale yellow to pale brown
pKa	-3.34±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.493
MDL	MFCD09878432

71701-92-3 - Risk and Safety

Risk Codes	R25 - Toxic if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S7/9 - S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37 - Wear suitable protective clothing and gloves. S38 - In case of insufficient ventilation, wear suitable respiratory equipment. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S51 - Use only in well ventilated areas.
UN IDs	UN 2811 6.1 / PGIII
WGK Germany	3
Hazard Class	6.1

71701-92-3 - Introduction

3-Bromo-2-choro-5-(trifluoromethyl)pyridine is an organic compound with the formula C6H2BrClF3N. It is a white crystalline powder with high thermal and chemical stability.

The compound has important applications in drug synthesis and pesticide synthesis. It can be used as an intermediate for the synthesis of biologically active compounds. For example, it can be used to synthesize antiviral drugs and pesticides, etc.

The 3-Bromo-2-chloro-5-(trifluoromethyl)pyridine can be prepared by different methods. A common method is to introduce bromine and chlorine atoms in the reaction by bromination and chlorination, respectively, starting with pyridine. Then, a trifluoromethyl group is introduced in a trifluoromethylation reaction. This synthesis is usually carried out under an inert atmosphere to ensure high selectivity and yield of the reaction.

The 3-Bromo-2-chloro-5-(trifluoromethyl)pyridine has limited safety information. It may be irritating to the eyes, respiratory system and skin. During use, care should be taken to avoid direct contact with skin and eyes. At the same time, appropriate protective measures should be taken during operation, such as wearing protective glasses, gloves and protective clothing.

In addition, during handling and storage, care should be taken to prevent contact with flammable materials and maintain good ventilation. When disposing of waste, local regulations should be followed and appropriate waste disposal methods should be adopted. It is best used and handled under the guidance of experienced chemists.

Last Update：2024-04-09 21:32:43