72678-19-4

72678-19-4 - Names and Identifiers

Name	4-Amino-3,5-dibromobenzotrifluoride
Synonyms	BUTTPARK 296-99 4-Amino-3,5-dibromobenzotrifluoride 4-AMINO-3,5-DIBROMOBENZOTRIFLUORIDE 2,6-DIBROMO-4-(TRIFLUOROMETHYL)ANILINE 2,6-Dibromo-4-(trifluoromethyl)aniline 2,6-Dibromo-4-(trifluoromethyl)aniline, 2,6-Dibromo-alpha,alpha,alpha-trifluoro-p-toluidine
CAS	72678-19-4
EINECS	623-441-6
InChI	InChI=1/C7H4Br2F3N/c8-4-1-3(7(10,11)12)2-5(9)6(4)13/h1-2H,13H2

72678-19-4 - Physico-chemical Properties

Molecular Formula	C7H4Br2F3N
Molar Mass	318.92
Density	1.9954 (rough estimate)
Melting Point	34-38°C(lit.)
Boling Point	64-65 °C (0.1 mmHg)
Flash Point	>230°F
Water Solubility	Insoluble in water.
BRN	6314196
pKa	-1.36±0.10(Predicted)
Storage Condition	Keep in dark place,Inert atmosphere,Room temperature
Refractive Index	1.4640 (estimate)
MDL	MFCD00068181

72678-19-4 - Risk and Safety

Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
UN IDs	2811
WGK Germany	3
HS Code	29214300
Hazard Note	Irritant
Hazard Class	6.1
Packing Group	III

72678-19-4 - Introduction

4-Amino-3,5-dibromobenzotrifluoride is an organic compound with the chemical formula C7H4Br2F3N. The following is a description of its nature, use, formulation and safety information:

Nature:
-Appearance: Colorless or light yellow solid
-Solubility: Soluble in organic solvents such as ethanol and dimethylformamide
-melting point: about 115-117 ℃
-Boiling point: about 285 ℃

Use:
4-Amino-3,5-dibromobenzotrifluoride has certain application value and is often used in the following aspects:
-As an intermediate in organic synthesis, it can be used to prepare other compounds, such as drugs, pesticides and dyes.
-In chemical research, it can be used as a reagent for deprotection reaction.

Preparation Method:
4-Amino-3,5-dibromobenzotrifluoride can generally be prepared by the following steps:
1.3,5-dibromobenzoic acid was used as raw material to prepare 3,5-dibromobenzoic acid ester by acidification reaction.
2.3,5-dibromobenzoic acid ester is reacted with nitrogen compound to decarboxylate to generate 3,5-dibromobenzene acetyl chloride.
3. react 3,5-dibromobenzotrifluoromethane with 3,5-dibromobenzotrifluoride to generate 4-Amino-3,5-dibromobenzotrifluoride.
4. The pure product can be obtained by crystallization or other purification methods.

Safety Information:
- 4-Amino-3,5-dibromobenzotrifluoride needs to take corresponding safety measures during operation and storage to avoid contact with skin and eyes.
-and to prevent inhalation or ingestion.
-Wear appropriate protective equipment such as chemical gloves, goggles and protective clothing during use.
-In the event of a possible accident or inadvertent contact, rinse immediately with water and seek medical attention.
-When handling the compound, please follow the safety procedures.

Last Update：2024-04-09 02:00:47