72925-16-7

72925-16-7 - Names and Identifiers

Name	(R)-1-Boc-pyrrolidine-3-carboxylic acid
Synonyms	BOC-L-B-PROLINE (3S)-BOC-BETA-PRO-OH (S)-1-N-BOC-BETA-PROLINE (R)-1-N-Boc-beta-proline S-1-BOC-PYRROLIDINE-3-CARBOXYLIC ACID (R)-n-Boc-pyrrolidine-3-carboxylic acid (R)-1-Boc-pyrrolidine-3-carboxylic acid (3S)-BOC-1-PYRROLIDINE-3-CARBOXYLIC ACID BOC-(3S)-1-PYRROLIDINE-3-CARBOXYLIC ACID (R)-1-tert-Butoxycarbonyl-pyrrolidine-3-carboxylic acid (3R)-1-(tertbutoxycarbonyl)pyrrolidine-3-carboxylic acid (S)-PYRROLIDINE-1,3-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER
CAS	72925-16-7
EINECS	674-617-4
InChI	InChI=1/C10H17NO4/c1-10(2,3)15-9(14)11-5-4-7(6-11)8(12)13/h7H,4-6H2,1-3H3,(H,12,13)/t7-/m1/s1

72925-16-7 - Physico-chemical Properties

Molecular Formula	C10H17NO4
Molar Mass	215.25
Density	1.201±0.06 g/cm3(Predicted)
Melting Point	138-143°C
Boling Point	337.2±35.0 °C(Predicted)
Flash Point	157.7°C
Solubility	Soluble in Dimethyl sulfoxide (DMSO).
Vapor Presure	2E-05mmHg at 25°C
pKa	4.47±0.20(Predicted)
Storage Condition	2-8°C
Refractive Index	1.502
MDL	MFCD03094727

72925-16-7 - Risk and Safety

Hazard Symbols	N - Dangerous for the environment
Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R50 - Very Toxic to aquatic organisms
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets.
UN IDs	UN 3077 9 / PGIII
WGK Germany	3
HS Code	29339900

72925-16-7 - Introduction

(R)-(R)-(acid) is an organic compound with the following properties:

1. Appearance:(R)-acid is a colorless solid.

2. Chemical properties: It is a pyrrolidine derivative with carboxyl group and protecting group (Boc,tert-butoxycarbonyl). It is stable at room temperature and can be dissolved in some polar solvents, such as dimethyl sulfoxide and dichloromethane.

3. uses:(R)-acid is commonly used in asymmetric synthesis reactions in organic synthesis. It can be used as a building block for chiral backbones for the synthesis of drugs, natural products and other biologically active compounds.

4. preparation method: a common preparation method is through 1-pyrrolidine methanol (pyrrolidine-1-carboxylic acid) and N-tert-butoxycarbonyl-L-alanine (N-tert-Boc-L-alloisoleucine acid) esterification reaction, and through acid hydrolysis to obtain the target product.

5. Safety information:(R)-acid is generally safe under normal use conditions, but as a chemical substance, it may cause harm to human health and the environment. Therefore, during handling and storage, safe operating procedures should be followed and contact with skin, eyes and mucous membranes should be avoided.

Last Update：2024-04-09 20:48:19