73290-22-9

Name	2-Bromo-5-iodopyridine
Synonyms	2-BROMO-5-IODOPYRIDINE 2-Bromo-5-iodopyridine 2-Bromo-5-Iodine Pyridine Pyridine, 2-bromo-5-iodo-
CAS	73290-22-9
EINECS	629-182-5
InChI	InChI=1/C5H3BrIN/c6-5-2-1-4(7)3-8-5/h1-3H
InChIKey	LLKRSJVPTKFSLS-UHFFFAOYSA-N

Molecular Formula	C5H3BrIN
Molar Mass	283.89
Density	2.347±0.06 g/cm3(Predicted)
Melting Point	121-123 °C (lit.)
Boling Point	278.6±20.0 °C(Predicted)
Flash Point	122.3°C
Vapor Presure	0.00714mmHg at 25°C
Appearance	White solid
Color	White to off-white
BRN	109100
pKa	-1.23±0.10(Predicted)
Storage Condition	Keep in dark place,Sealed in dry,Room Temperature
Sensitive	Light Sensitive
Refractive Index	1.665
MDL	MFCD03095201

Risk Codes	R22 - Harmful if swallowed R37/38 - Irritating to respiratory system and skin. R41 - Risk of serious damage to eyes
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/39 -
WGK Germany	3
HS Code	29333990
Hazard Class	IRRITANT

introduction	2-bromo -5-iodopyridine is white or off-white solid powder under normal temperature and pressure, which can be soluble in common organic solvents, such as dimethyl sulfoxide, N,N-dimethyl formamide, dichloromethane, ethyl acetate, methanol, ethanol and other alcohol solvents, but the solubility in water is poor. It can be used as an intermediate in organic synthesis.
use	2-bromo-5-iodopyridine is a common organic synthesis intermediate, mainly used for pyridine-containing drug molecules and bioactive molecules Structural modification and derivatization. Among them, the iodine and bromine on the pyridine ring can be obtained by Suzuki coupling reaction, and the pyridine ring is connected to the product of the aromatic ring at positions 2 and 5.
Synthesis method	For the synthesis of 2-bromo-5-iodopyridine, the conventional synthesis method is Starting from 2, 5-dibromopyridine, use n-butyl lithium to remove the bromine on the pyridine ring to obtain the corresponding aryl lithium reagent, then add iodine to obtain the target product 2-bromo-5-iodopyridine.

Last Update：2024-04-09 20:52:54

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Mobile: 86+15671228036
QQ: 2853786052

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Spot supply

Product Name: 2-Bromo-5-iodopyridine Visit Supplier Webpage Request for quotation
CAS: 73290-22-9
Tel: 18301782025
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QQ: 3008007409

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73290-22-9

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