73368-35-1
benzyl-alpha-13C cyanide
CAS: 73368-35-1
Molecular Formula: C8H7N
73368-35-1 - Names and Identifiers
| Name | benzyl-alpha-13C cyanide |
| Synonyms | BENZYL-ALPHA-13C CYANIDE benzyl-alpha-13C cyanide phenyl(acetonitrile-2-13c) |
| CAS | 73368-35-1 |
73368-35-1 - Physico-chemical Properties
| Molecular Formula | C8H7N |
| Molar Mass | 118.16 |
| Density | 1.024g/mLat 25°C |
| Melting Point | −24°C(lit.) |
| Boling Point | 233-234°C(lit.) |
| Flash Point | 215°F |
| Refractive Index | n20/D 1.523(lit.) |
73368-35-1 - Risk and Safety
| Risk Codes | R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed. R36/38 - Irritating to eyes and skin. R26 - Very Toxic by inhalation R24 - Toxic in contact with skin R22 - Harmful if swallowed |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36/37 - Wear suitable protective clothing and gloves. S28 - After contact with skin, wash immediately with plenty of soap-suds. |
| UN IDs | UN 2470 6.1/PG 3 |
| WGK Germany | 3 |
73368-35-1 - Introduction
benzyl-alpha-13C cyanide is a phenylacetonitrile compound containing the 13C isotope. Its molecular formula is C7H6 ^ 13CH2CN.
Nature:
benzyl-alpha-13C cyanide is a colorless liquid with a special carbon isotope label. It is an important carbon isotope labeling reagent in organic chemistry.
Use:
benzyl-alpha-13C cyanide are commonly used in nuclear magnetic resonance (NMR) studies as carbon labeling reagents to study and trace the transformation pathways, metabolism and reaction mechanisms of compounds. It can also be used to prepare other isotopically labeled compounds.
Preparation Method:
The preparation of benzyl-alpha-13C cyanide is generally obtained by a nucleoside acylation reaction. First, 13C isotope-labeled bromoacetic acid and bromobenzene undergo a substitution reaction to produce benzyl-alpha-13C cyanide. The benzyl-alpha-13C cyanide is then reacted with sodium sulfite to give the final product.
Safety Information:
There is little information on the toxicity and safety of benzyl-alpha-13C cyanide, but in general, phenylacetonitrile compounds can cause irritation to the eyes, skin and respiratory tract, and direct contact should be avoided. In the use of the process to take good measures to avoid inhalation of gas, pay attention to personal protective measures. When handling such compounds, the necessary safety operation procedures should be followed, and safety assessment and risk control should be carried out according to the actual situation. In order to ensure safety, please use under the guidance of people with chemical expertise.
Nature:
benzyl-alpha-13C cyanide is a colorless liquid with a special carbon isotope label. It is an important carbon isotope labeling reagent in organic chemistry.
Use:
benzyl-alpha-13C cyanide are commonly used in nuclear magnetic resonance (NMR) studies as carbon labeling reagents to study and trace the transformation pathways, metabolism and reaction mechanisms of compounds. It can also be used to prepare other isotopically labeled compounds.
Preparation Method:
The preparation of benzyl-alpha-13C cyanide is generally obtained by a nucleoside acylation reaction. First, 13C isotope-labeled bromoacetic acid and bromobenzene undergo a substitution reaction to produce benzyl-alpha-13C cyanide. The benzyl-alpha-13C cyanide is then reacted with sodium sulfite to give the final product.
Safety Information:
There is little information on the toxicity and safety of benzyl-alpha-13C cyanide, but in general, phenylacetonitrile compounds can cause irritation to the eyes, skin and respiratory tract, and direct contact should be avoided. In the use of the process to take good measures to avoid inhalation of gas, pay attention to personal protective measures. When handling such compounds, the necessary safety operation procedures should be followed, and safety assessment and risk control should be carried out according to the actual situation. In order to ensure safety, please use under the guidance of people with chemical expertise.
Last Update：2024-04-10 22:29:15
