737797-28-3
3,4-Difluorophenylzinc bromide
CAS: 737797-28-3
Molecular Formula: C6H3BrF2Zn
737797-28-3 - Names and Identifiers
737797-28-3 - Physico-chemical Properties
| Molecular Formula | C6H3BrF2Zn |
| Molar Mass | 258.37 |
| Exposure Limit | ACGIH: TWA 50 ppm; STEL 100 ppm (Skin)OSHA: TWA 200 ppm(590 mg/m3)NIOSH: IDLH 2000 ppm; TWA 200 ppm(590 mg/m3); STEL 250 ppm(735 mg/m3) |
| Sensitive | Air Sensitive |
737797-28-3 - Risk and Safety
| Hazard Class | 4.3 |
737797-28-3 - Introduction
3,4-Difluorophenylzinc bromide is an organic zinc compound. Its chemical formula is C6H3BrCl2Zn and its molecular weight is 292.25g/mol. It is a colorless to pale yellow liquid, soluble in organic solvents such as chloroform and dimethyl sulfoxide at room temperature.
This compound is mainly used in the field of organic synthesis. It can be used as an important organic synthesis reagent for the construction of C- C bonds or C- X bonds. In the synthesis of aromatic compounds, the 3,4-dichlorophenyl group can be introduced by reacting the 3,4-Difluorophenylzinc bromide with an aryl halide. In addition, it can also be used to synthesize drugs, pesticides and other biologically active molecules.
The preparation of 3,4-Difluorophenylzinc bromide is generally carried out by chemical synthesis methods. A common preparation method is the reaction of 3,4-dichlorophenyl bromide with anhydrous zinc powder in an organic solvent. The reaction is usually carried out under an inert gas atmosphere, and good yield and purity can be obtained by controlling the reaction temperature and reaction time.
Pay attention to safety when using 3,4-Difluorophenylzinc bromide. It is an organic zinc compound, which has certain toxicity and corrosiveness. Wear appropriate personal protective equipment, including goggles, gloves and lab clothes. This should be done in a well-ventilated laboratory environment and avoid contact with skin or eyes. In the case of accidental contact, rinse immediately with plenty of water and seek medical help.
This compound is mainly used in the field of organic synthesis. It can be used as an important organic synthesis reagent for the construction of C- C bonds or C- X bonds. In the synthesis of aromatic compounds, the 3,4-dichlorophenyl group can be introduced by reacting the 3,4-Difluorophenylzinc bromide with an aryl halide. In addition, it can also be used to synthesize drugs, pesticides and other biologically active molecules.
The preparation of 3,4-Difluorophenylzinc bromide is generally carried out by chemical synthesis methods. A common preparation method is the reaction of 3,4-dichlorophenyl bromide with anhydrous zinc powder in an organic solvent. The reaction is usually carried out under an inert gas atmosphere, and good yield and purity can be obtained by controlling the reaction temperature and reaction time.
Pay attention to safety when using 3,4-Difluorophenylzinc bromide. It is an organic zinc compound, which has certain toxicity and corrosiveness. Wear appropriate personal protective equipment, including goggles, gloves and lab clothes. This should be done in a well-ventilated laboratory environment and avoid contact with skin or eyes. In the case of accidental contact, rinse immediately with plenty of water and seek medical help.
Last Update：2024-04-09 15:18:01
