74-95-3

74-95-3 - Names and Identifiers

Name	Dibromomethane
Synonyms	Dibromomethane Dibromo methane MethyleneBromide Methylene bromide 1,1-dibroMoMethane 1,1-dibromomethane methylene dibromide DIBROMOMETHANE FOR SYNTHESIS Anti-DBH antibody produced in goat Dibromomethane, Stabilized with 50ppm BHT dopamine beta-hydroxylase (dopamine beta-monooxygenase)
CAS	74-95-3
EINECS	200-824-2
InChI	InChI=1/CH2Br2/c2-1-3/h1H2

74-95-3 - Physico-chemical Properties

Molecular Formula	CH2Br2
Molar Mass	173.83
Density	2.477g/mLat 25°C(lit.)
Melting Point	-52 °C
Boling Point	96-98°C(lit.)
Flash Point	96-98°C
Water Solubility	0.1 g/100 mL (20 ºC)
Solubility	11.7g/l
Vapor Presure	34.9 mm Hg ( 20 °C)
Vapor Density	6.05 (vs air)
Appearance	Liquid
Color	Clear colorless to slightly brown
Merck	14,6061
BRN	969143
Storage Condition	Store below +30°C.
Stability	Stable. Incompatible with strong oxidizing agents, aluminium, magnesium. Reacts violently with potassium.
Refractive Index	n20/D 1.541(lit.)
Physical and Chemical Properties	Characteristics of colorless or light yellow liquid. melting point -52.5 ℃ boiling point 97 ℃ relative density 2.4970 refractive index 1.5420 solubility miscibility with ethanol, ether and acetone
Use	Used as a raw material for organic synthesis, can be used as a solvent, refrigerant, flame retardant and antiknock agent components, medicine used as a disinfectant and town

74-95-3 - Risk and Safety

Risk Codes	R20 - Harmful by inhalation R52/53 - Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment. R39/23/24/25 - R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed. R11 - Highly Flammable
Safety Description	S24 - Avoid contact with skin. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36/37 - Wear suitable protective clothing and gloves. S16 - Keep away from sources of ignition. S7 - Keep container tightly closed.
UN IDs	UN 2664 6.1/PG 3
WGK Germany	2
RTECS	PA7350000
TSCA	Yes
HS Code	2903 39 15
Hazard Class	6.1
Packing Group	III
Toxicity	LD50 orally in Rabbit: 108 mg/kg LD50 dermal Rabbit > 4000 mg/kg

74-95-3 - Nature

Open Data Verified Data

colorless or light yellow liquid. Relative density (d20)2. 4970. Melting Point -52.5 °c. Boiling point 97. Refractive index 5420. Viscosity (20 ℃)1. 02mPa.s. Miscible with ethanol, ether and acetone. Each lOOOg of water soluble dibromomethane 11.70g (15 °c), 11.93g (30 °c). Non-flammable. The critical temperature is 310 ℃ and the critical pressure is 7. 194MPa.

Last Update：2024-01-02 23:10:35

74-95-3 - Preparation Method

Open Data Verified Data

The tribromomethane method first uses arsenic trioxide to react with liquid alkali to prepare sodium arsenite solution. Heating the sodium arsenite solution to 65 ℃, slowly adding bromoform under stirring. After all the addition is completed, stirring and refluxing are continued for 4H to complete the reaction, and the reactants are poured into 5-6 times of water, the oil was removed and fractionated. Then wash to neutral, with calcium chloride dehydration, distillation, product.
The dichloromethane method is industrially prepared by reacting anhydrous CHz Clz/anhydrous AIBr3 with HBr under catalysis, and chlorobromomethane is also produced.
bromochloromethane hydrogen bromide method.

Last Update：2022-01-01 10:13:51

74-95-3 - Use

Open Data Verified Data

raw materials for organic synthesis. It can be used as solvent, refrigerant, flame retardant and antiknock component; It can be used as disinfectant and sedative in medicine; It can also be used as pesticide, myclobutanazole and other organic synthesis.

Last Update：2022-01-01 10:13:51

74-95-3 - Safety

Open Data Verified Data

toxicity was similar to that of dichloromethane. The maximum allowable concentration in air is 20 × 10 -6. Inhalation of high concentrations of dibromomethane can cause Head Pain, dizziness, Vomit, and often cause visual impairment, severe cases cause movement disorders, cramps, Coma; More serious, as a result of neurological disorders caused by mania, and even lethargy and death, anatomy found intracerebral hemorrhage. Can be absorbed through the skin and poisoning.
Acute poisoning should be immediately away from the scene, symptomatic treatment. Protective equipment should be worn during operation, and the workshop should be well ventilated and the equipment should be sealed.

Last Update：2022-01-01 10:13:52

74-95-3 - Reference Information

NIST chemical information	information provided by: webbook.nist.gov (external link)
EPA chemical substance information	information provided by: ofmpeb.epa.gov (external link)
Use	dibromomethane is a raw material for the preparation of bactericides mycloxazole and myxazole. raw materials for organic synthesis. It can be used as a component of solvents, refrigerants, flame retardants and antiknock agents; It is used as a disinfectant and analgesic in the pharmaceutical industry. It is also used for pesticide myclobutanil and other organic synthesis. used as raw material for organic synthesis, used as solvent, refrigerant, flame retardant and antiknock component, used as disinfectant and disinfectant in medicine used as raw material for organic synthesis, can be used as refrigerant/flame retardant and other components used as solvent, also used in organic synthesis
production method	1. The sodium arsenite solution was prepared by first reacting arsenic trioxide with liquid alkali. The sodium arsenite solution was heated to 65 ℃ and gradually added with bromoform under stirring, the reaction was completed, and the reactant was poured into 5-6 times of water, and the oil was extracted and fractionated. Then wash to neutral, with calcium chloride dehydration, distillation, product. Raw material consumption quota: bromoform 8300kg/t, arsenic trioxide 1200kg/t, 40% liquid alkali 16500kg/t. Dichloromethane method in industry, anhydrous CH2Cl2 in anhydrous AlBr3 catalyzed reaction with HBr, but also produce methyl chloride. 3. Bromochloromethane-hydrogen bromide method. The preparation method is prepared by the reaction of dichloromethane with bromine or the reaction of bromochloromethane with hydrogen bromide. Reaction equation: CH2Cl2 + Br2 → CH2Br2 + Cl2CH2BrCl + HBr → CH2Br2 + HCl
category	toxic substances
toxicity grade	high toxicity
Acute toxicity	oral-rat LD50: 108 mg/kg; Subcutaneous-mouse LD50: 3738 mg/kg
flammability hazard characteristics	bromide gas from thermal decomposition
storage and transportation characteristics	The warehouse is ventilated and dried at low temperature; It is stored separately from oxidants and food additives
extinguishing agent	dry powder, foam, carbon dioxide, sand.
Occupational Standard	TWA 10 mg/m3; Tel 10 mg/m3
toxic substance data	information provided by: pubchem.ncbi.nlm.nih.gov (external link)