76104-14-8

76104-14-8 - Names and Identifiers

Name	(2Z)-(hydroxyimino)(4-methoxyphenyl)ethanenitrile
Synonyms	α-Hydroxyimino-4-methoxyphenylacetonitrile (2Z)-(hydroxyimino)(4-methoxyphenyl)ethanenitrile (Z,E)-2-(HYDROXYIMINO)-2-(4-METHOXYPHENYL)ACETONITRILE
CAS	76104-14-8
InChI	InChI=1/C9H8N2O2/c1-13-8-4-2-7(3-5-8)9(6-10)11-12/h2-5,12H,1H3/b11-9+

76104-14-8 - Physico-chemical Properties

Molecular Formula	C9H8N2O2
Molar Mass	176.17
Density	1.149g/cm³
Boling Point	332.539°C at 760 mmHg
Flash Point	154.914°C
Vapor Presure	0mmHg at 25°C
Storage Condition	2-8℃
Refractive Index	1.545

76104-14-8 - Risk and Safety

Hazard Symbols	Xi - Irritant
Hazard Note	Irritant

76104-14-8 - Introduction

(2Z)-(hydroxyimino)(4-methoxyphenyl)ethanenitrile is an organic compound whose chemical formula is C9H9NO2. The following is its nature, use, preparation and safety information:

Nature:
-Appearance: (2Z)-(hydroxyimino)(4-methoxyphenyl)ethanenitrile is a solid substance, the common form is white crystals.
-Solubility: It has low solubility in water and is soluble in some common organic solvents, such as ethanol, methanol and dimethyl sulfoxide.
-Melting point: Its melting point is about 170-174°C.

Use:
(2Z)-(hydroxyimino)(4-methoxyphenyl)ethanenitrile has important applications in the field of organic synthesis:
-It is an important intermediate that can be used to synthesize various nitrogen-containing organic compounds.
-it can be used as a catalyst, reducing agent, oxidant and complexing agent, etc., to participate in a variety of organic synthesis reaction.
-It also has certain applications in the synthesis of drugs and pesticides.

Preparation Method:
(2Z)-(hydroxyimino)(4-methoxyphenyl)ethanenitrile has many preparation methods. The following is one of the common synthetic routes:
1. First, p-methoxybenzoic acid is reacted with hydroxamic acid to generate p-methoxybenzonitrile.
2. Then, through a redox reaction, p-methoxybenzonitrile is converted into the imine of p-methoxyacetophenone.
3. Finally, the imine of p-methoxyacetophenone is converted into (2Z)-(hydroxyimino)(4-methoxyphenyl)ethanenitrile by acyl chloride reaction and nitrosamide reaction.

Safety Information:
(2Z)-(hydroxyimino)(4-methoxyphenyl) The specific hazards and safety information ethanenitrile may vary depending on the specific environment and conditions of use. Therefore, when using or handling this substance, it is recommended to follow the following safety measures:
-Use personal protective equipment, such as laboratory gloves, protective glasses and protective masks.
-Use in a well-ventilated place and avoid inhalation or contact with skin.
-Avoid contact with strong oxidizing agents or strong reducing agents.
-Disposal of waste in a suitable waste treatment facility.

It is important to note that before using or handling any chemical substance, it is best to read the relevant chemical literature carefully and strictly follow the relevant laboratory safety procedures.

Last Update：2024-04-09 21:01:54