762262-09-9

762262-09-9 - Names and Identifiers

Name	2-Methoxypyridne-4-boronic acid
Synonyms	4-Borono-2-methoxypyridine 2-Methoxypyridne-4-boronic acid 2-Methoxypyridine-4-boronicacid 2-METHOXYPYRIDINE-4-BORONIC ACID 2-Methoxypyridine-4-boronic acid 2-METHOXYPYRIDIN-4-YLBORONIC ACID 2-METHOXY-4-PYRIDINYLBORONIC ACID 2-Methoxyl-4-pyridine boronic ester 2-METHOXY-4-PYRIDINE-4-BORONIC ACID Boronic acid, B-(2-methoxy-4-pyridinyl)-
CAS	762262-09-9
InChI	InChI=1/C6H8BNO3/c1-11-6-4-5(7(9)10)2-3-8-6/h2-4,9-10H,1H3

762262-09-9 - Physico-chemical Properties

Molecular Formula	C6H8BNO3
Molar Mass	152.94
Density	1.24±0.1 g/cm3(Predicted)
Boling Point	325.7±52.0 °C(Predicted)
pKa	7.11±0.10(Predicted)
Storage Condition	Inert atmosphere,Store in freezer, under -20°C
Refractive Index	1.523

762262-09-9 - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	R37/38 - Irritating to respiratory system and skin. R41 - Risk of serious damage to eyes R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39 - Wear eye / face protection. S36 - Wear suitable protective clothing.
HS Code	29339900
Hazard Note	Irritant

762262-09-9 - Introduction

2-Methoxypyridne-4-boronic acid is an organic boron compound with the chemical formula C6H8BNO3. It has the form of a white to pale yellow crystalline solid.

2-Methoxypyridne-4-boronic acid is widely used in the field of organic synthesis. It is an important boronic acid reagent and can be used as one of the ligands in Suzuki-Miyaura cross-coupling reactions, reacting with organic halides or organic boronic esters to generate the corresponding coupling products. In addition, it can also be used as an intermediate of fine chemicals for the synthesis of drugs, dyes and other compounds.

The method of preparing 2-Methoxypyridne-4-boronic acid is usually carried out by methylation reaction. A common preparation method is to react 2-tolylpyridine with trimethylborane, and then react the resulting intermediate with boric acid to finally obtain the target product.

2-Methoxypyridne-4-boronic acid is relatively stable at room temperature, but avoid direct sunlight. It is a flammable substance and needs to be kept away from open flames and high temperatures. During the operation, attention should be paid to protective measures, such as wearing protective glasses and gloves. At the same time, avoid contact with strong oxidants and acidic substances during storage.

Last Update：2024-04-09 21:11:58