765927-71-7

765927-71-7 - Names and Identifiers

Name	3'-N,N-Di(desmethyl)-3'-N-formyl Azithromycin
Synonyms	N-formyl-N-di(demethyl)-AZT Azithromycin Impurity M(BP) 3′-(N,N-Didemethyl)-3′-N-formylazithromycin 3'-N,N-Di(desMethyl)-3'-N-forMyl AzithroMycin 3'-N,N-Di(desmethyl)-3'-N-formyl Azithromycin 3'-N,N-Di(desmethyl)-3'-N-formyl Azithromycin(Azithromycin EP Impurity M) (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[(2,6-Dideoxy-3-C-Methyl-3-O-Methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptaMethyl-11-[[3,4,6-trideoxy-3-(forMylaMino)-β-D-xylo-hexop
CAS	765927-71-7
EINECS	204-888-2

765927-71-7 - Physico-chemical Properties

Molecular Formula	C37H68N2O13
Molar Mass	748.95
Density	1.21±0.1 g/cm3(Predicted)
Melting Point	108-110°C
Boling Point	871.6±65.0 °C(Predicted)
Solubility	DMSO (Slightly), Methanol (Sparingly)
Appearance	Solid
Color	White to Pale Beige
pKa	13.16±0.70(Predicted)
Storage Condition	-20°C Freezer

765927-71-7 - Introduction

3 '-N,N-bis (desmethyl)-3-n-formylazithromycin is an Azithromycin Impurity, also known as Azithromycin Impurity M. It is a structural analog of azithromycin with a slightly different chemical structure and properties.

Its properties include:
-Chemical structure: 3 '-N,N-bis (desmethyl)-3-n-formylazithromycin is a derivative of azithromycin, two desmethyl groups and one formyl group are attached to specific positions of the azithromycin molecule.
-Appearance: Usually white or off-white crystalline solid.
-Melting point: About 162-165 ° C.

3 '-N,N-di (desmethyl)-3-n-formylazithromycin has certain uses in the field of medicine, and is mainly used as a synthetic intermediate of drugs. It can react with other compounds to generate substituted azithromycin drugs with specific effects.

Preparation method, the specific synthesis method may vary due to the actual needs of research and development. In General, 3 '-N,N-bis (desmethyl)-3-n-formylazithromycin can be synthesized by introducing a desmethyl group and a formyl group at appropriate positions in the azithromycin molecule.

As for safety information, because Azithromycin Impurity M is a compound, it is necessary to follow relevant safety procedures when using and handling. Possible safety information includes, but is not limited to, the following:
-Toxicity: No specific information has been reported on the toxicity of 3 '-N,N-bis (desmethyl)-3-n-formylazithromycin, however, it needs to be properly handled and handled to avoid direct contact with skin, eyes or inhalation of its dust.
-Combustibility: It is necessary to avoid contact with combustibles and keep away from fire sources.
-Storage: Should be stored in a sealed container, away from high temperature, fire and oxidizing agents.

Last Update：2024-04-09 22:09:11