768358-04-9

768358-04-9 - Names and Identifiers

Name	3-[(2-fluorophenoxy)methyl]piperidine
Synonyms	CHEMBRDG-BB 4004496 3-[(2-fluorophenoxy)methyl]piperidine 3-(2-FLUORO-PHENOXYMETHYL)-PIPERIDINE Piperidine, 3-[(2-fluorophenoxy)methyl]-
CAS	768358-04-9
InChI	InChI=1/C12H16FNO/c13-11-5-1-2-6-12(11)15-9-10-4-3-7-14-8-10/h1-2,5-6,10,14H,3-4,7-9H2

768358-04-9 - Physico-chemical Properties

Molecular Formula	C12H16FNO
Molar Mass	209.26
Density	1.067g/cm³
Boling Point	305.06°C at 760 mmHg
Flash Point	138.296°C
Vapor Presure	0.001mmHg at 25°C
Storage Condition	Room Temprature
Refractive Index	1.496

768358-04-9 - Risk and Safety

Hazard Symbols	Xi - Irritant
Hazard Class	IRRITANT

768358-04-9 - Introduction

3-[(2-fluorophenoxy)methyl]piperidine is an organic compound whose chemical formula is C13H16FNO. The following is a description of its nature, use, formulation and safety information:

Nature:
-Appearance: colorless or yellowish liquid
-Solubility: Soluble in organic solvents such as chloroform, dichloromethane and alcohols
-Melting point:-9°C
-Boiling point: 261-262°C
-Density: 1.054 g/mL at 25°C

Use:
- 3-[(2-fluorophenoxy)methyl]piperidine are mainly used as intermediates and reagents in organic synthesis.
-It can be used to synthesize drugs, pesticides and other organic compounds.
-It is also used as a solvent in chemical research and laboratory work.

Preparation Method:
The preparation of 3-[(2-fluorophenoxy)methyl]piperidine can be completed by the following steps:
1. First, 2-fluorophenol is reacted with sodium hydroxide to generate sodium 2-fluorophenol.
2. Next, sodium 2-fluorophenate is reacted with a chloromethyl compound to produce 2-fluorophenyl methyl ether.
3. Finally, 2-fluorophenyl methyl ether was reacted with piperidine to give 3-[(2-fluorophenoxy)methyl]piperidine.

Safety Information:
- 3-[(2-fluorophenoxy)methyl]piperidine is an organic compound and should be handled with care to avoid contact with skin, eyes and mucous membranes.
-Wear appropriate personal protective equipment such as protective gloves, glasses and lab coats during use.
-During storage, it should be placed in a cool, dry and well-ventilated place, away from fire and oxidizing agents.
-If swallowed or entered by mistake, seek medical attention immediately and show the package or technical information to the doctor.

Last Update：2024-04-09 21:01:54