769944-51-6
R-2-(4-chlorophenyl)piperazine
CAS: 769944-51-6
Molecular Formula: C10H13ClN2
769944-51-6 - Names and Identifiers
| Name | R-2-(4-chlorophenyl)piperazine |
| Synonyms | 2-(4-Chlorphenyl)piperazin 2-(4-Chlorophenyl)piperazine R-2-(4-chlorophenyl)piperazine piperazine, 2-(4-chlorophenyl)- (2S)-2-(4-chlorophenyl)piperidine (2R)-2-(4-Chlorophenyl)piperazine Piperazine, 2-(4-chlorophenyl)-, (2R)- |
| CAS | 769944-51-6 |
| InChI | InChI=1/C11H14ClN/c12-10-6-4-9(5-7-10)11-3-1-2-8-13-11/h4-7,11,13H,1-3,8H2/t11-/m0/s1 |
769944-51-6 - Physico-chemical Properties
| Molecular Formula | C10H13ClN2 |
| Molar Mass | 196.68 |
| Density | 1.095g/cm3 |
| Boling Point | 288.1°C at 760 mmHg |
| Flash Point | 128.1°C |
| Vapor Presure | 0.00238mmHg at 25°C |
| Refractive Index | 1.536 |
769944-51-6 - Introduction
R-2-(4-chlorophenyl)piperazine(R-2-(4-chlorophenyl)piperazine) is an organic compound with the chemical formula C10H14ClN2. The following is an introduction to some of its properties, uses, methods and safety information:
Nature:
-Appearance: Common white crystalline solid;
-Solubility: Soluble in polar solvents such as ethanol and acetone, slightly soluble in water;
-melting point: about 155-158 ℃;
-Stability: Stable at room temperature and pressure, but decomposition reaction may occur when encountering light, heat and oxygen.
Use:
-Drug synthesis: R-2-(4-chlorophenyl)piperazine is a derivative of piperazine compounds, which is commonly used in drug synthesis in the pharmaceutical field, such as the preparation of antipsychotics and antidepressants;
-Chemical research: It can also be used as a reagent or intermediate in organic synthesis and participate in some organic reactions;
-Scientific research: In some studies, the R-2-(4-chroophenyl) piperazine is also used to detect and measure certain compounds.
Preparation Method:
R-2-(4-chlorophenyl)piperazine has a variety of synthetic methods, one of the commonly used methods is by 4-chlorobenzoyl chloride and piperazine reaction under alkaline conditions. This synthetic process requires proper control because the choice of reactants and conditions can produce different isomers.
Safety Information:
-Toxicity: R-2-(4-chroophenyl) piperazine may have certain toxicity at a certain dose. Exposure or inhalation of large amounts can cause adverse reactions and even life-threatening. Therefore, care should be taken during use to avoid direct contact with skin, eyes and respiratory tract.
-Hazard: The substance needs to be properly stored and handled to prevent it from reacting with inflammables, oxidants, etc., causing a fire or explosion.
-Toxicity data and operation guidelines: Refer to the safety data sheet (SDS) and related operation guidelines when using to ensure correct safety and operation methods.
Nature:
-Appearance: Common white crystalline solid;
-Solubility: Soluble in polar solvents such as ethanol and acetone, slightly soluble in water;
-melting point: about 155-158 ℃;
-Stability: Stable at room temperature and pressure, but decomposition reaction may occur when encountering light, heat and oxygen.
Use:
-Drug synthesis: R-2-(4-chlorophenyl)piperazine is a derivative of piperazine compounds, which is commonly used in drug synthesis in the pharmaceutical field, such as the preparation of antipsychotics and antidepressants;
-Chemical research: It can also be used as a reagent or intermediate in organic synthesis and participate in some organic reactions;
-Scientific research: In some studies, the R-2-(4-chroophenyl) piperazine is also used to detect and measure certain compounds.
Preparation Method:
R-2-(4-chlorophenyl)piperazine has a variety of synthetic methods, one of the commonly used methods is by 4-chlorobenzoyl chloride and piperazine reaction under alkaline conditions. This synthetic process requires proper control because the choice of reactants and conditions can produce different isomers.
Safety Information:
-Toxicity: R-2-(4-chroophenyl) piperazine may have certain toxicity at a certain dose. Exposure or inhalation of large amounts can cause adverse reactions and even life-threatening. Therefore, care should be taken during use to avoid direct contact with skin, eyes and respiratory tract.
-Hazard: The substance needs to be properly stored and handled to prevent it from reacting with inflammables, oxidants, etc., causing a fire or explosion.
-Toxicity data and operation guidelines: Refer to the safety data sheet (SDS) and related operation guidelines when using to ensure correct safety and operation methods.
Last Update：2024-04-09 20:49:11
