77690-92-7
Feruloylspinosin, 6'''-
CAS: 77690-92-7
Molecular Formula: C38H40O18
77690-92-7 - Names and Identifiers
77690-92-7 - Physico-chemical Properties
| Molecular Formula | C38H40O18 |
| Molar Mass | 784.71 |
| Density | 1?+-.0.1 g/cm3(Predicted) |
| Melting Point | 194-197°C |
| Boling Point | 1029.8±65.0 °C(Predicted) |
| Specific Rotation(α) | -45.2 (c, 0.38 in MeOH) |
| Solubility | Insuluble (2.2E-3 g/L) (25 °C) |
| Appearance | Pale yellow crystalline powder |
| pKa | 5.71±0.40(Predicted) |
| Storage Condition | 2-8℃ |
| MDL | MFCD28964219 |
| Physical and Chemical Properties | Pale yellow crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, comes from jujuba Mill.var.spinosa, Ziziphus of jujuba Mill.var. |
77690-92-7 - Reference
| Reference Show more | 1. Gao Hongning, Yin Yi, Yan Guojun. UPLC-UV-ELSD determination of semen ziziphi spinosae saponin A, semen ziziphi spinosae saponin B, spinoside and 6 '''-ferulic acid Pinosol in semen ziziphi spinosae from different habitats [J]. China Contemporary Medicine, 2021,28(06):8-12. 2. [IF = 1.813] Zhan Liang-Hui et al."Soporific Effect of Modified Suanzaoren division and Its Effects on the Expression of CCK-8 and Orexin-A. Evid-Based Compl Alt. 2020;2020:6984087 |
77690-92-7 - Reference Information
| overview | 6-feruloylspinol belongs to jujube seed flavone, jujube seed flavone (mainly spinol and 6-feruloylspinol) is one of the active substances that exert sedation and hypnosis in jujube seed. The total flavonoids of Semen Ziziphi Spinosae is an important component of Semen Ziziphi Spinosae. Modern pharmacological studies have shown that it has a sedative and hypnotic effect on animals, and is one of the active substances in Semen Ziziphi Spinosae. |
| biological activity | 6-Feruloylspinosin is a flavone isolated from Ziziphus jujuba seeds. In rat hippocampal neurons, 6-Feruloylspinosin can penetrate the blood-brain barrier and enhance the mRNA expression of GABAAα1, GABAAα5 and GABABR1. |
| chemical properties | light yellow crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from jujuba Mill.var.spinosa, Ziziphus jujujuba Mill.var. |
| use | 6-feruoylspinol has anti-allergic effects. used for content determination/identification/pharmacological experiments and other pharmacological effects: jujuba Mill.var.spinosa of jujuba Mill.var. of jujuba Mill.var. Last Update：2024-04-09 21:54:55
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77690-92-7
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