78603-95-9
(S)-(-)-2-Amino-3-methyl-1,1-diphenyl-1-butanol
CAS: 78603-95-9
Molecular Formula: C17H21NO
78603-95-9 - Names and Identifiers
| Name | (S)-(-)-2-Amino-3-methyl-1,1-diphenyl-1-butanol |
| Synonyms | 1,1-Diphenyl-L-valinol 4-anilino-3-(methylamino)butan-1-ol )-2-Amino-3-methyl-1,1-diphenyl-1-butanol (s)-2-amino-1,1-diphenyl-3-methyl-1-butanol (2S)-2-Amino-3-methyl-1,1-diphenylbutan-1-ol (S)-(-)-2-AMINO-3-METHYL-1,1-DIPHENYL-1-BUTANOL (S)-(-)-2-Amino-3-methyl-1,1-diphenyl-1-butanol Benzenemethanol, alpha-[(1S)-1-amino-2-methylpropyl]-alpha-phenyl- (S)-2-Amino-1,1-diphenyl-3-methyl-1-butanol, 1,1-Diphenyl-L-valinol |
| CAS | 78603-95-9 |
| InChI | InChI=1/C17H21NO/c1-13(2)16(18)17(19,14-9-5-3-6-10-14)15-11-7-4-8-12-15/h3-13,16,19H,18H2,1-2H3/t16-/m0/s1 |
78603-95-9 - Physico-chemical Properties
| Molecular Formula | C17H21NO |
| Molar Mass | 255.36 |
| Density | 1.074±0.06 g/cm3(Predicted) |
| Melting Point | 95-99°C(lit.) |
| Boling Point | 424.7±40.0 °C(Predicted) |
| Flash Point | 210.6°C |
| Vapor Presure | 5.73E-08mmHg at 25°C |
| pKa | 11.20±0.50(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
| Refractive Index | 1.576 |
| MDL | MFCD01318248 |
78603-95-9 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| HS Code | 29062990 |
78603-95-9 - Introduction
(S)-(-)-2-Amino-3-methyl-1,1-diphenyl-1-butanol, also known as (S)-(-)-2-Amino-3-methyl-1,1-diphenyl-1-butanol, is a chiral compound. It has the following properties:
Appearance: Colorless to light yellow solid
Molecular formula: C18H21NO
Molecular weight: 267.37g/mol
melting point: 80-82 ℃
Boiling point: 410 ℃ (predicted value)
Density: 1.08g/cm³
(S)-(-)-2-Amino-3-methyl-1,1-diphenyl-1-butanol has a wide range of applications, including drug synthesis, chiral catalysts and optically active reagents. It can be used to synthesize compounds with pharmaceutical activity, especially for the preparation of chiral drugs. In addition, it can also be used as a chiral catalyst to promote specific chemical reactions in organic synthesis; at the same time, it also has applications in optically active reagents and asymmetric synthesis.
The method of preparing (S)-(-)-2-Amino-3-methyl-1,1-diphenyl-1-butanol is usually by reacting as follows:
(S)-2-amino-1-butene and dimethyl benzene dicarbonate are subjected to an addition reaction to obtain (S)-(-)-2-Amino-3-methyl-1,1-diphenyl-1-butanol.
With regard to safety information, specific toxicity and hazard assessments of this compound are rarely reported, and therefore laboratory safety practices should be strictly followed. (S)-(-)-2-Amino-3-methyl-1,1-diphenyl-1-butanol may be irritating to the skin and eyes, so contact with skin and eyes should be avoided during operation. In case of accidental contact, immediately flush the affected area with plenty of water and seek professional medical help. During handling and storage, avoid contact with oxidants, strong acids and alkalis to avoid fire or explosion.
Appearance: Colorless to light yellow solid
Molecular formula: C18H21NO
Molecular weight: 267.37g/mol
melting point: 80-82 ℃
Boiling point: 410 ℃ (predicted value)
Density: 1.08g/cm³
(S)-(-)-2-Amino-3-methyl-1,1-diphenyl-1-butanol has a wide range of applications, including drug synthesis, chiral catalysts and optically active reagents. It can be used to synthesize compounds with pharmaceutical activity, especially for the preparation of chiral drugs. In addition, it can also be used as a chiral catalyst to promote specific chemical reactions in organic synthesis; at the same time, it also has applications in optically active reagents and asymmetric synthesis.
The method of preparing (S)-(-)-2-Amino-3-methyl-1,1-diphenyl-1-butanol is usually by reacting as follows:
(S)-2-amino-1-butene and dimethyl benzene dicarbonate are subjected to an addition reaction to obtain (S)-(-)-2-Amino-3-methyl-1,1-diphenyl-1-butanol.
With regard to safety information, specific toxicity and hazard assessments of this compound are rarely reported, and therefore laboratory safety practices should be strictly followed. (S)-(-)-2-Amino-3-methyl-1,1-diphenyl-1-butanol may be irritating to the skin and eyes, so contact with skin and eyes should be avoided during operation. In case of accidental contact, immediately flush the affected area with plenty of water and seek professional medical help. During handling and storage, avoid contact with oxidants, strong acids and alkalis to avoid fire or explosion.
Last Update：2024-04-09 21:11:58
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Product Name: (S)-(-)-2-Amino-3-methyl-1,1-diphenyl-1-butanol Visit Supplier Webpage Request for quotationTel: 18301782025
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Multiple Specifications
Product Name: (S)-(-)-2-Amino-3-methyl-1,1-diphenyl-1-butanol Visit Supplier Webpage Request for quotationTel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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