79622-11-0 - Names and Identifiers
79622-11-0 - Physico-chemical Properties
79622-11-0 - Upstream Downstream Industry
79622-11-0 - Introduction
m-PEG8-Tos(m-PEG8-Tos) is a compound with a specific chemical structure. The following is a description of the nature, use, preparation and safety information of the m-PEG8-Tos:
Nature:
-chemical formula: C18H34O8S
-Molecular weight: 418.52g/mol
-Appearance: White or off-white solid
-Melting point: about 52-55 degrees Celsius
Use:
m-PEG8-Tos are widely used in the fields of chemistry and biomedicine, and their main uses include but are not limited to the following:
1. In drug development, m-PEG8-Tos is often used as a functional reagent for polyethylene glycol modified drugs, which can increase the water solubility, stability and biological activity of drugs.
2. In biomedical research, m-PEG8-Tos can be used to prepare nanoparticles, microspheres and construct biocompatible materials for drug delivery, gene delivery and bioimaging.
3. In chemical synthesis, m-PEG8-Tos can be used as condensation reagents or functionalization reagents to introduce polyethylene glycol modification groups in organic synthesis reactions.
Method:
The preparation method of m-PEG8-Tos usually involves the following steps:
1. P-toluenesulfonic acid (p-Tosylate) is reacted with heptaethylene glycol (PEG8) under alkaline conditions.
2. Heating and stirring are required during the reaction, and the reaction is usually carried out under an inert atmosphere.
3. After the reaction is completed, the pure m-PEG8-Tos product is obtained by appropriate purification methods, such as crystallization, volatile solvent, etc.
Safety Information:
The use of m-PEG8-Tos requires attention to its safety. Here are some common safety guidelines:
1. Avoid direct contact with skin and eyes, such as accidental contact, please rinse with plenty of water.
2. During the operation, appropriate personal protective measures should be taken, such as wearing gloves, safety glasses and protective clothing.
3. Please pay attention to well-ventilated laboratory conditions when using.
4. Avoid inhalation or ingestion of the substance.
5. If necessary, please follow the relevant Safety Data Sheet (Safety Data Sheet) and Operation Guide.
Last Update：2024-04-10 22:43:14