Name | GABAB receptor antagonist 1 |
Synonyms | GABAB receptor antagonist 1 3-Butenoic acid, 4-[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]-2-oxo- |
CAS | 797-17-1 |
Molecular Formula | C18H24O4 |
Molar Mass | 304.38 |
Density | 1.125±0.06 g/cm3(Predicted) |
Melting Point | 136-139 °C (decomp) |
Boling Point | 404.3±37.0 °C(Predicted) |
pKa | 2.26±0.54(Predicted) |
In vitro study | (E)-GABAB receptor antagonist 1 (compound 14) decreases agonist GABA-induced maximal effect of IP3 production in HEK293 cells overexpressing GABAB receptors and Gqi9 proteins without changing the EC 50 . |