8-Methyl-1,7-dihydro-purin-6-one - Names and Identifiers
Name | 8-Methyl-7H-purin-6-ol
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Synonyms | 8-METHYLHYPOXANTHINE 8-Methyl-7H-purin-6-ol 8-methyl-1H-purin-6(7H)-one 8-Methyl-1,7-dihydro-purin-6-one 1,7-Dihydro-8-Methyl-6H-Purin-6-One 8-methyl-5,9-dihydro-6H-purin-6-one 8-Methyl-6,7-dihydro-1H-purin-6-one 6H-Purin-6-One,1,7-Dihydro-8-Methyl- 6H-Purin-6-one, ,7-dihydro-8-methyl- 6H-PURIN-6-ONE, 1,7-DIHYDRO-8-METHYL- 6H-Purin-6-one, 1,7-dihydro-8-methyl- (9CI)
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CAS | 30467-02-8
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InChI | InChI=1/C6H6N4O/c1-3-9-4-5(10-3)7-2-8-6(4)11/h2H,1H3,(H2,7,8,9,10,11) |
8-Methyl-1,7-dihydro-purin-6-one - Physico-chemical Properties
Molecular Formula | C6H6N4O
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Molar Mass | 150.14 |
Density | 1.72±0.1 g/cm3(Predicted) |
Melting Point | 288-289 °C (decomp) |
Boling Point | 606.7±28.0 °C(Predicted) |
Flash Point | 249.048°C |
Vapor Presure | 0mmHg at 25°C |
pKa | 8.91±0.70(Predicted) |
Storage Condition | 2-8°C |
Refractive Index | 1.758 |
8-Methyl-1,7-dihydro-purin-6-one - Introduction
8-Methyl-7H-purin-6-ol is an organic compound with the chemical formula C6H8N4O and a molecular weight of 164.15g/mol. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: 8-Methyl-7H-purin-6-ol is a white solid.
-Solubility: Soluble in water and some organic solvents.
-Melting point: About 260-262 degrees Celsius.
Use:
-Pharmaceutical field: 8-Methyl-7H-purin-6-ol is an important raw material that can be used to synthesize drugs and compounds, and has a wide range of biological activities. It is often used as an intermediate for antiviral drugs, immunomodulators, and anticancer drugs.
-Laboratory applications: The structure and properties of the compound make it useful for laboratory synthesis and research.
Method:
8-Methyl-7H-purin-6-ol can be prepared in a variety of ways. The following is a common synthetic route:
1. Starting from 3,7-dimethylpurine, a methyl group was introduced at the 7-position by nucleophilic aromatic exchange reaction.
2. After methylation, the methyl group at the 7-position is oxidized to an alcohol group through an oxidation reaction.
3. The compound was further purified and crystallized to obtain pure 8-Methyl-7H-purin-6-ol.
Safety Information:
Specific Safety information for the-8-methyll-7h-purin-6-ol can be found in the Safety Data Sheet (SDS). When using or handling the compound, refer to the relevant safety practices.
Last Update:2024-04-09 02:00:45