8-Methylquinolin-2(1H)-one

8-Methylquinolin-2(1H)-one - Names and Identifiers

Name	8-methylquinolin-2(1H)-one
Synonyms	8-methylquinolin-2-ol 8-methylquinolin-2(1H)-one 8-Methyl-2(1H)-quinolinone 8-Methylquinolin-2(1H)-one 2-Hydroxy-8-methylquinoline 2(1H)-Quinolinone, 8-methyl-
CAS	4053-36-5

8-Methylquinolin-2(1H)-one - Physico-chemical Properties

Molecular Formula	C10H9NO
Molar Mass	159.18
Density	1.150±0.06 g/cm3(Predicted)
Melting Point	219-220 °C
Boling Point	339.3±42.0 °C(Predicted)
pKa	11.81±0.70(Predicted)
Storage Condition	Sealed in dry,Room Temperature

8-Methylquinolin-2(1H)-one - Introduction

Nature:
- 8-methylquinolin-2(1H)-one is a solid, common form is white crystals.
-It has a fragrant taste.
-The compound is soluble in solvents such as dichloromethane, chloroform and ethanol.

Use:
- 8-methylquinolin-2(1H)-one is commonly used as a starting material or intermediate in organic synthesis.
-It can be used to synthesize other organic compounds, such as drugs, pesticides and dyes.
-The compound also has antiviral, antitumor and antioxidant properties, and may have potential biological activity.

Preparation Method:
-The commonly used preparation method is to react 2-methylpyridine with acid chloride, and then perform hydroxide treatment.
-Specifically, 2-methylpyridine can be first reacted with acid chloride to generate an amide compound, and then the amide is converted into a ketone through a base-catalyzed hydroxide reaction.

Safety Information:
-Normal laboratory and chemical safety procedures need to be followed.
-Since 8-methylquinolin-2(1H)-one also has certain toxicity, direct contact with skin and inhalation of its dust should be avoided.
-When using or handling this compound, avoid contact with dangerous chemicals such as strong oxidants and strong acids.
-In the event of contact or misuse, seek medical attention immediately and bring the compound's safety data sheet to provide the required information to the doctor.

Please note that the information provided above is for reference only. For specific applications and experimental operations, it is recommended to carry out in a professional environment, and take corresponding safety measures according to the actual situation.

Last Update：2024-04-09 21:04:16