8-Oxo-2-Deoxyguanosine
8-Oxo-2-Deoxyguanosine
CAS: 88847-89-6
Molecular Formula: C10H13N5O5
8-Oxo-2-Deoxyguanosine - Names and Identifiers
| Name | 8-Oxo-2-Deoxyguanosine |
| Synonyms | 8-Oxo-2-Deoxyguanosine 2'-Deoxy-8-oxoguanosine 2'-Deoxy-8-oxo-D-guanosine 2'-Deoxy-8-hydroxyguanosine 8-HYDROXY-2'-DEOXYGUANOSINE 8-Oxo-7,8-dihydrodeoxyguanosine 8-Oxo-7,8-dihydro-2'-deoxyguanosine 7,8-Dihydro-8-oxo-2'-deoxyguanosine 8-Oxo-7,8-dihydro-2μ-deoxyguanosine, 8-Oxo-dG |
| CAS | 88847-89-6 |
8-Oxo-2-Deoxyguanosine - Physico-chemical Properties
| Molecular Formula | C10H13N5O5 |
| Molar Mass | 283.24 |
| Density | 2.25±0.1 g/cm3(Predicted) |
| Melting Point | 217-220°C |
| Solubility | Soluble in DMSO (up to 10 mg/ml). |
| Appearance | White to off-white solid. |
| Color | Off-white |
| pKa | 7.86±0.20(Predicted) |
| Storage Condition | 2-8°C |
| Stability | Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month. |
| In vitro study | 8-Hydroxy-2'-deoxyguanosine (8-OHdG) is a good biomarker for risk assessment of various cancers and degenerative diseases. The biomarker 8-Hydroxy-2'-deoxyguanosine (8-OHdG) or 8-oxodG has been a pivotal marker for measuring the effect of endogenous oxidative damage to DNA and as a factor of initiation and promotion of carcinogenesis. The biomarker has been used to estimate the DNA damage in humans after exposure to cancer-causing agents, such as tobacco smoke, asbestos fibers, heavy metals, and polycyclic aromatic hydrocarbons. |
8-Oxo-2-Deoxyguanosine - Risk and Safety
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| RTECS | MF8782675 |
| HS Code | 29349990 |
8-Oxo-2-Deoxyguanosine - Reference
| Reference Show more | 1. Fan Yanling, Xia Xiaoyu, Jia douyong, etc. Protective effect and mechanism of Angelica sinensis polysaccharide on subacute renal injury induced by D-galactose in mice [J]. Chinese Journal of Traditional Chinese Medicine, 2015, 40(21):4229-4233. 2. Fan, Yanling, et al. "Mechanism of ginsenoside Rg1 renal protection in a mouse model of d-galactose-induced subacerdage." Pharmaceutical biology 54.9 (2016): 1815-1821.https:// doi.org/10.3109/13880209.2015.1129543 |
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Multiple Specifications
Product Name: 8-Oxo-2-Deoxyguanosine Visit Supplier Webpage Request for quotationCAS: 88847-89-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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