8-aminoquinolin-4-ol
7-bromoquinolin-4-ol
CAS: 82121-06-0
Molecular Formula: C9H6BrNO
8-aminoquinolin-4-ol - Names and Identifiers
| Name | 7-bromoquinolin-4-ol |
| Synonyms | 126205 BUTTPARK 89 1-98 BUTTPARK 100 1-52 8-aminoquinolin-4-ol 7-Bromo-4-quinolinol 7-bromoquinolin-4-ol 4-Quinolinol, 7-bromo- 7-bromo-4-hydroxyquinoline 7-BROMO-4-HYDROXYQUINOLINE |
| CAS | 82121-06-0 |
| EINECS | 804-508-0 |
| InChI | InChI=1/C9H6BrNO/c10-6-1-2-7-8(5-6)11-4-3-9(7)12/h1-5H,(H,11,12) |
| InChIKey | GGCBEWNXEGDQAP-UHFFFAOYSA-N |
8-aminoquinolin-4-ol - Physico-chemical Properties
| Molecular Formula | C9H6BrNO |
| Molar Mass | 224.05 |
| Density | 1.705±0.06 g/cm3(Predicted) |
| Melting Point | 279-281 °C |
| Boling Point | 370.7±22.0 °C(Predicted) |
| Flash Point | 178.013°C |
| Vapor Presure | 0mmHg at 25°C |
| pKa | 3.83±0.40(Predicted) |
| Storage Condition | Inert atmosphere,Room Temperature |
| Refractive Index | 1.718 |
8-aminoquinolin-4-ol - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R22 - Harmful if swallowed R41 - Risk of serious damage to eyes |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39 - Wear eye / face protection. |
| WGK Germany | 3 |
8-aminoquinolin-4-ol - Introduction
7-bromoquinolin-4-ol is an organic compound with the chemical formula C9H6BrNO. It is a white to pale yellow crystalline solid with a bitter taste. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: White to light yellow crystalline solid
-Melting point: 130-134°C
-Boiling point: 429.4°C
-solubility: soluble in alcohol, ether, ketone and other organic solvents, insoluble in water
-Properties: It is a stable compound with good stability to air and light
Use:
-Chemical reagents: can be used as catalysts and intermediates in organic synthesis
-Drugs: Can be used to synthesize drugs, hormones and bioactive compounds
Preparation Method:
7-bromoquinolin-4-ol is typically synthesized:
1. quinoline and bromine reaction, bromination reaction under the appropriate reaction conditions, the generation of 7-bromoquinoline.
2. 7-bromoquinolin-4-ol is obtained by reacting 7-bromoquinolin-4-ol with hydroxide under alkaline conditions.
Safety Information:
- 7-bromoquinolin-4-ol is an organic compound, which should be used in accordance with general laboratory operation and safety regulations.
-It may cause irritation to the eyes, skin and respiratory tract. Avoid direct contact with skin and eyes.
-Care should be taken to use personal protective equipment such as lab gloves, goggles and protective clothing during operation.
-In case of any discomfort, discontinue use immediately and seek professional medical advice.
Nature:
-Appearance: White to light yellow crystalline solid
-Melting point: 130-134°C
-Boiling point: 429.4°C
-solubility: soluble in alcohol, ether, ketone and other organic solvents, insoluble in water
-Properties: It is a stable compound with good stability to air and light
Use:
-Chemical reagents: can be used as catalysts and intermediates in organic synthesis
-Drugs: Can be used to synthesize drugs, hormones and bioactive compounds
Preparation Method:
7-bromoquinolin-4-ol is typically synthesized:
1. quinoline and bromine reaction, bromination reaction under the appropriate reaction conditions, the generation of 7-bromoquinoline.
2. 7-bromoquinolin-4-ol is obtained by reacting 7-bromoquinolin-4-ol with hydroxide under alkaline conditions.
Safety Information:
- 7-bromoquinolin-4-ol is an organic compound, which should be used in accordance with general laboratory operation and safety regulations.
-It may cause irritation to the eyes, skin and respiratory tract. Avoid direct contact with skin and eyes.
-Care should be taken to use personal protective equipment such as lab gloves, goggles and protective clothing during operation.
-In case of any discomfort, discontinue use immediately and seek professional medical advice.
Last Update：2024-04-09 15:18:00
