8000-48-4
Eucalyptus Oil
CAS: 8000-48-4
Molecular Formula: C10H18O
8000-48-4 - Names and Identifiers
8000-48-4 - Physico-chemical Properties
| Molecular Formula | C10H18O |
| Molar Mass | 154.25 |
| Density | 0.909g/mLat 25°C |
| Boling Point | 200°C |
| Flash Point | 135°F |
| Appearance | Liquid |
| Color | Colourless to pale yellow |
| Refractive Index | n20/D 1.46 |
| Physical and Chemical Properties | Colorless to light yellow liquid. There is a smell like camphor and borneol. Relative density (25/25 °c), melting point not lower than -15.4 °c. Refractive index 1.4580-1.4700(20 °c). Optical rotation -5 ° to 5 °. Practically insoluble in water, soluble in ethanol. |
| Use | It is used in the preparation of cough suppressant, mouthwash, pesticide ointment and the essence of toothpaste, tooth powder, candy, etc. |
8000-48-4 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | R10 - Flammable R38 - Irritating to the skin |
| Safety Description | S16 - Keep away from sources of ignition. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| UN IDs | UN 1993 3/PG 3 |
| WGK Germany | 2 |
| RTECS | LE2530000 |
| HS Code | 33012960 |
| Hazard Class | 3.2 |
| Packing Group | III |
| Toxicity | The acute oral LD50 value of eucalyptol was reported as 2480 mg/kg in the rat (Jenner, Hagan, Taylor, Cook & Fitzhugh, 1964). The acute dermal LD50 in rabbits exceeded 5 g/kg (Moreno, 1973). |
8000-48-4 - Nature
Open Data Verified Data
colorless or light yellow transparent liquid, with a special cooling aroma of eucalyptus flavor and pungent cooling medicine odor, has a certain antiseptic bactericidal effect. Melting Point -15.4 °c. Insoluble in water, soluble in ethanol and oil.
Last Update：2024-01-02 23:10:35
8000-48-4 - Preparation Method
Open Data Verified Data
The tender leaves of eucalyptus globulus or other eucalyptus trees were collected, and the oil was extracted by steam distillation. Can be divided into two kinds of atmospheric pressure method and pressure method. The atmospheric pressure method is to add a cooking pot to the lower part of the oil drum, and steam is directly generated from the pot to achieve the purpose of distilling eucalyptus oil. The pressurized method is to supply steam from an industrial boiler, and the inlet pressure is 0.2~0. 4MPa, the internal pressure of 0.05MPa.
Last Update：2022-01-01 11:15:35
8000-48-4 - Use
Open Data Verified Data
Eucalyptus oil is one of the world's largest production of essential oils, according to the use can be divided into medical oil, industrial oil and perfume oil three. Eucalyptus oil is mainly used in medicine, health products, such as toothpaste, tooth powder, powder, medical soap, chewing gum, Cough syrup, cooling oil, fan cream, etc. It is also used in a small amount in the preparation of certain daily chemical products. Can also be used for flotation of mineral sand, as well as detergent additives and fungicides.
Last Update：2022-01-01 11:15:35
8000-48-4 - Reference Information
| FEMA | 2466 | EUCALYPTUS OIL (EUCALYPTUS GLOBULUS LABILLE) |
| EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
| Introduction | Eucalyptus oil is one of the most commonly used essential oils. With the increasing popularity of sweets and chewing gums, one of the main uses of Eucalyptus oil is as a food additive. Synthetic spices have a new impact and a clean infection, and have a great impact on the cosmetics industry (such as toothpaste and oral cleaning products) and other household cleaning products, also affects the fragrance of the perfume. Eucalyptus oil is also used in the pharmaceutical industry as an antibacterial agent, especially in the treatment of respiratory infections and other similar diseases. |
| Main component | contains volatile oil, and the main components in eucalyptus oil are: & beta;-cineole, & alpha; & beta;,Y-terpineol, d,& beta;-pinene, pinene acetate, Orange. In addition, it still contains a variety of components such as aryl aldehyde. It also contains rutin, quercetin, quercitrin, eucalyptol, tannin, resin and bitter quality. |
| Source | volatile oil obtained from leaves of eucalyptus globulus or other plants belonging to the same genus by steam distillation. Plant morphology: large tree, up to more than 10 meters. The bark was usually exfoliated and pale blue-gray; The branches were slightly 4-prism-shaped, with glandular points and narrow wings on the ribs. Leaf Type 2: old trees bearing normal leaves, leaves sickle-shaped, linear, long-pointed, base broadly wedge-shaped and slightly oblique; Young plants and new branches bearing abnormal leaves, single leaf opposite, leaf blade Oval-ovoid, sessile, Apex short-pointed, base shallowly cordate; Both leaves were covered densely with white powder and green-gray below, with distinct glandular dots on both sides. Flowers usually solitary in leaf axilla or 2-3 clumped, sessile or with very short and flattened sessile; Calyx tube with ribs and small nodules, with blue-white wax; petals confluent with sepals into a cap, yellowish-white, many in stamens, separated in sequence; Style thicker. Capsule cup-shaped, with 4 ribs and inconspicuous tumor or groove. |
| efficacy and function | eucalyptus oil can dispense wind, relieve fever, remove dampness and detoxify. It is a kind of medicine, eucalyptus oil can be used as food flavor, the most important thing in food flavor is safety, eucalyptus oil has high safety, which is very good for our health, however, eucalyptus oil also has a lot of benefits for us. In fact, many foods now contain eucalyptus oil as an active ingredient, which has many benefits for our health. Eucalyptus oil for our health also has a lot of benefits, in many of the drinks contain the active ingredients of eucalyptus oil, we drink this drink, the effect of quickly replenishing energy can be achieved. And Eucalyptus oil is very good for our health. Eucalyptus oil is very useful for our health, because eucalyptus oil has a bactericidal effect, of course, we can use eucalyptus oil in many places, can purify the toxic and harmful substances in the air, for our health has a very good health care effect. |
| field of application | Eucalyptus oil is also used in the pharmaceutical industry as an antibacterial agent, especially in the treatment of respiratory tract infections and other similar diseases. This is a commonly used and very effective ingredient in sinus sprays and is also commonly used in syrups, ointments to alleviate the Dyspnea problem. Similarly, eucalyptus oil has also been widely transported to the field of flavor massage, make people excited. It can also be used to reduce skin inflammation and relieve rheumatic pain. Eucalyptus oil can be used for massage, hydrotherapy, and also for sports massage (which can relieve muscle fatigue). Eucalyptus oil can also be used in pesticides. |
| side effects | improper use of eucalyptus oil may cause abdominal burning, Nausea Vomit, dizziness Fatigue, or cold and moist extremities, dyspnea and other poisoning phenomenon, if serious, may lead to death, need everyone to pay attention. The cause of side effects: Because eucalyptus oil will cause gastrointestinal and digestive tract mucosa irritation. Eucalyptus oil contains a lot of cineole, rutin, quercetin and other ingredients, these ingredients will stimulate the digestive tract mucosa, inhibit the respiratory center, causing discomfort. |
| content analysis | accurately weigh about 3g of sample previously dried with anhydrous sodium sulfate, transfer into a 25mm x 150mm test tube. 2.100g of molten O-Cresol with a melting point above 30 ° C. (the effect of wet cresol is not good) is added. The mixture was stirred with a thermometer until crystallization and the highest crystallization temperature was noted. The test tube is slowly warmed to allow complete melting of the solid, then the test tube is inserted into an instrument for determining the freezing point and is slowly cooled to the onset of crystallization, or the temperature is lowered to the known point described above. The tube was rubbed up and down the tube wall with a thermometer and agitated strongly until crystals were formed. Continuous agitation and friction cause the temperature to rise. The highest temperature was taken as the freezing point. The above procedure was repeated until the two results did not differ by more than 0.1 °c. The percentage content of cineole was then determined according to the content determination method in "cineole (03554). |
| toxicity | LD50 2480mg/kg (rat, oral). GRAS(FEMA). |
| usage limit | GB 2760-96: standard, GMP. FDA,§172? 510(2000), moderate limit. FEMA(mg/kg): Soft drink 1.7; Cold drink 0.5~50; Candy 130; Alcohol 10; Baking |
| Use | is mainly used for toothpaste, tooth powder, body powder, medicinal soap, cooling oil, wind repellant and other health pharmaceutical products. It can also be used in small amounts in the preparation of certain daily chemical product flavors. as a food spice. One of the world's top ten varieties of essential oils. Can be used for the preparation of toothpaste, 1:3 sugar and other food flavors. The usage amount is 130mg/kg in candy; 76mg/kg in baked food; 1.7mg/kg in soft drinks; 0.5~50mg/kg in alcohol in cold drinks 1.0mg/kg. Can also be used as cooling oil, wind cream and oral inflammation, rhinitis medication raw materials. flavorant. Mainly used for the preparation of chewing gum, cough sugar flavor. for the treatment of neuralgia for the preparation of cough suppressant, mouthwash, pesticide ointment and the preparation of toothpaste, tooth powder, candy and other flavors. |
| production method | , fresh leaves of camphor tree and camphor tree were obtained by steam distillation. The yield ranged from 2% to 3%. It is mainly produced in Spain, Portugal, Congo and South America. China's Yunnan, Guangdong, Guangxi also have a large number of production, for the world's top ten essential oils (production) one.|
| category | relatively flammable liquid |
| toxicity grade | poisoning |
| Acute toxicity | oral-rat LD50: 2480 mg/kg |
| stimulation data | Skin-rabbit 500 mg/24 h moderate |
| flammability hazard characteristics | in case of open flame, high temperature, flammable oxidant; Combustion stimulus smoke |
| storage and transportation characteristics | The warehouse is ventilated and dried at low temperature; Stored separately from oxidants and acids |
| extinguishing agent | dry powder, dry sand, carbon dioxide, foam, 1211 extinguishing agent |
Last Update：2024-04-09 21:32:08
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