808142-23-6
Bis[2-(diphenylphosphino)phenyl] ether oxide
CAS: 808142-23-6
Molecular Formula: C36H28O3P2
808142-23-6 - Names and Identifiers
| Name | Bis[2-(diphenylphosphino)phenyl] ether oxide |
| Synonyms | DPEPO Vortioxetine Impurity 73 Bis[2-((oxo)diphenylphosphino)phenyl] ether Bis[2-(diphenylphosphino)phenyl] ether oxide (oxybis(2,1-phenylene))bis(diphenylphosphine oxide) Phosphine oxide, 1,1'-(oxydi-2,1-phenylene)bis[1,1-diphenyl- Bis[2-[(oxo)diphenylphosphino]phenyl] Ether (purified by sublimation) |
| CAS | 808142-23-6 |
808142-23-6 - Physico-chemical Properties
| Molecular Formula | C36H28O3P2 |
| Molar Mass | 570.55 |
| Density | 1.28±0.1 g/cm3(Predicted) |
| Melting Point | 280℃ |
| Boling Point | 753.3±60.0 °C(Predicted) |
| Appearance | powder |
| Odor | White powder/crystals |
| Maximum wavelength(λmax) | 292nm(CH2Cl2)(lit.) |
| Storage Condition | Sealed in dry,Room Temperature |
808142-23-6 - Introduction
Bis[2-(diphenylphosphino)phenyl] ether oxide, also known as DPEPhos, is an organic compound. Its chemical formula is C24H21OP and its molecular weight is 356.39g/mol.
DPEPhos has the following properties:
1. Appearance: colorless to yellowish solid.
2. Melting point: About 150-154 ° C.
3. Solubility: Soluble in common organic solvents, such as chloroform, dimethylformamide and dichloromethane.
DPEPhos has several applications in organic synthesis:
1. Ligand of metal catalyst: DPEPhos can coordinate with metal catalyst to form a complex, which is used to catalyze organic reactions, such as hydrogenation, coupling reaction and asymmetric catalytic reaction.
2. Transition metal catalyzed hydrogenation reaction: DPEPhos is coordinated with transition metal to form a catalyst, which is used to hydrogenate unsaturated compounds, such as olefins and carbonyl compounds.
3. Asymmetric catalytic reaction: Due to its adjustable stereo structure, DPEPhos can be used in asymmetric catalytic reaction with chiral ligands to prepare chiral organic compounds.
There are usually two methods for preparing DPEPhos:
1. Oxidation method: DPEPhos can be prepared by oxidation of phenyl diphosphine.
2. Phenyldiphosphine direct addition method: phenyldiphosphine is directly added to fluoride or other appropriate reagents to generate DPEPhos.
Safety information about DPEPhos, because it involves the synthesis of organic compounds and laboratory use, there may be certain risks to the human body and the environment. When using and handling, it is necessary to follow appropriate laboratory practices and take appropriate safety measures to prevent contact, inhalation and ingestion. Detailed safety information can be found in the safety data sheets of the relevant chemicals.
DPEPhos has the following properties:
1. Appearance: colorless to yellowish solid.
2. Melting point: About 150-154 ° C.
3. Solubility: Soluble in common organic solvents, such as chloroform, dimethylformamide and dichloromethane.
DPEPhos has several applications in organic synthesis:
1. Ligand of metal catalyst: DPEPhos can coordinate with metal catalyst to form a complex, which is used to catalyze organic reactions, such as hydrogenation, coupling reaction and asymmetric catalytic reaction.
2. Transition metal catalyzed hydrogenation reaction: DPEPhos is coordinated with transition metal to form a catalyst, which is used to hydrogenate unsaturated compounds, such as olefins and carbonyl compounds.
3. Asymmetric catalytic reaction: Due to its adjustable stereo structure, DPEPhos can be used in asymmetric catalytic reaction with chiral ligands to prepare chiral organic compounds.
There are usually two methods for preparing DPEPhos:
1. Oxidation method: DPEPhos can be prepared by oxidation of phenyl diphosphine.
2. Phenyldiphosphine direct addition method: phenyldiphosphine is directly added to fluoride or other appropriate reagents to generate DPEPhos.
Safety information about DPEPhos, because it involves the synthesis of organic compounds and laboratory use, there may be certain risks to the human body and the environment. When using and handling, it is necessary to follow appropriate laboratory practices and take appropriate safety measures to prevent contact, inhalation and ingestion. Detailed safety information can be found in the safety data sheets of the relevant chemicals.
Last Update：2024-04-10 22:29:15
808142-23-6 - Nature
| melting point | 280℃ |
| boiling point | 753.3±60.0 °C(Predicted) |
| density | 1.28±0.1 g/cm3(Predicted) |
| storage conditions | Sealed in dry,Room Temperature |
| morphology | powder |
| maximum wavelength (& lambda;max) | 292nm(CH2Cl2)(lit.) |
| Odor | White powder/crystals |
| Absorption | λmax?388 nm in?CH2Cl2 |
Last Update：2024-04-10 22:29:15
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