820971-67-3

820971-67-3 - Names and Identifiers

Name	1-Azetidinecarboxylic acid, 3-[(methoxymethylamino)carbonyl]-,1,1-dimethylethyl ester
Synonyms	1-Boc-3-[methoxy(methyl)carbamoyl]azetidine 1-Boc-3-[Methoxy(Methyl)carbaMoyl]azetidine 1-Boc-N-methoxy-N-methylazetidine-3-carboxamide tert-butyl 3-(methoxy(methyl)carbamoyl)azetidine-1-carboxylate 1-Azetidinecarboxylic acid, 3-[(methoxymethylamino)carbonyl]... 3-[(Methoxymethylamino)carbonyl]-1-azetidinecarboxylicacid,1,1-dimethylethylester 1-Azetidinecarboxylic acid, 3-[(methoxymethylamino)carbonyl]-,1,1-dimethylethyl ester 1-Azetidinecarboxylic acid, 3-[(MethoxyMethylaMino)carbonyl]-, 1,1-diMethylethyl ester
CAS	820971-67-3

820971-67-3 - Physico-chemical Properties

Molecular Formula	C11H20N2O4
Molar Mass	244.29
Storage Condition	2-8°C

820971-67-3 - Introduction

1-Azetidinecarboxylic acid, 3-[(methoxymethylamino)carbonyl]-,1,1-dimethylethyl ester, also known as 1-Azetidinecarboxylic acid, 3-[(methoxymethylamino)carbonyl]-,1,1-dimethylethyl ester (abbreviated as Boc-azetidine ester), is an organic compound. Its properties are as follows:

1. Chemical formula: C12H22N2O4
2. molecular weight: 258.32g/mol
3. Appearance: colorless to light yellow solid
4. melting point: about 80-82°C
5. Solubility: Soluble in some organic solvents (such as dimethyl sulfoxide, dichloromethane and dichloroethane).

Boc-azetidine methyl ester is mainly used as a protecting group in organic synthetic chemistry, and is often used to protect amine groups. It can be used as an intermediate in the synthesis of drugs, natural products and other organic compounds. Its application range is very wide.

The preparation method of Boc-azetidine methyl ester includes the following steps:

1. The reaction of 1-azbutylamine and formyl chloride gives 1-azobutyl formamide.
2. The obtained 1-azobutyl formamide was reacted with methanol and methyl sodium to obtain N-methoxy-1-azobutyl formamide.
3. Finally, the obtained N-methoxy-l-azobutyl formamide was reacted with N,N-dimethylformamide to obtain the final product Boc-azetidine methyl ester.

For safety information on Boc-azetidine methyl ester, use of this compound in the laboratory should follow good laboratory practices and personal protective equipment. This compound may be irritating and can be harmful to the eyes, skin and respiratory system. Avoid direct exposure to skin and eyes and ensure good ventilation during handling. During use, storage and disposal, please follow the relevant safety procedures and regulations.

Last Update：2024-04-09 21:54:55