82827-09-6

82827-09-6 - Names and Identifiers

Name	1(2H)-Isoquinolinone,6-bromo-
Synonyms	6-Bromo-2H-isoquinoL 6-Bromoisoquinolin-1-one 6-BROMOISOQUINOLIN-1-ONE 6-BROMO-2H-ISOQUINOLIN-1-ONE 6-bromoisoquinolin-1(2H)-one 6-Bromo-2H-isoquinolin-1-one 6-bromo-2H-isoquinoline-1-one 1(2H)-Isoquinolinone,6-bromo- 6-broMo-1,2-dihydroisoquinolin-1-one 6-broMo-1,2-dihydro-1-oxoisoquinoline
CAS	82827-09-6

82827-09-6 - Physico-chemical Properties

Molecular Formula	C9H6BrNO
Molar Mass	224.05
Density	1.620±0.06 g/cm3(Predicted)
Boling Point	442.6±45.0 °C(Predicted)
Flash Point	221.498 °C
pKa	12.20±0.20(Predicted)
Storage Condition	2-8°C

82827-09-6 - Introduction

1(2H)-Isoquinolinone,6-bromo-is an organic compound with the chemical formula C9H6BrNO. The following is a description of its nature, use, formulation and safety information:

Nature:
1. Appearance: 1(2H)-Isoquinolinone,6-bromo-white to light yellow solid.
2. solubility: can be dissolved in some organic solvents, such as dimethyl sulfoxide and dichloromethane.
3. Melting point: about 170-173°C.
4. Insoluble in water.

Use:
1. Drug intermediates: 1(2H)-Isoquinolinone,6-bromo-is used as an intermediate for some drugs, such as for the synthesis of anti-cancer drugs.
2. Organic synthesis: It can be used as a starting point for organic synthesis.

Preparation Method:
There are many methods for preparing 1(2H)-Isoquinolinone,6-bromo-. The following is one of the commonly used methods:
isoquinoline and bromine are added into the reaction flask, then an appropriate amount of anhydrous dimethyl sulfoxide is added as a solvent, the reaction mixture is heated to the reaction temperature, after a period of reaction, after the reaction is completed, 1(2H)-Isoquinolinone,6-bromo-is obtained by crystallization or column chromatography and other methods-. Specific reaction conditions and operation methods can be adjusted according to actual needs.

Safety Information:
1. 1(2H)-Isoquinolinone,6-bromo-has the risk of explosion at high temperature, please pay attention to proper storage and operation.
2. Please pay attention to protective measures when using, such as wearing suitable gloves, glasses and protective clothing.
3. avoid inhalation of its dust, avoid contact with skin and eyes.
4. Please pay attention to a well-ventilated working environment during use to prevent the inhalation of steam or dust.
5. In case of accidental contact or inhalation, immediately stay away from the scene and seek medical help.

Note: The above content is for reference only. Please follow the safety procedures when using chemicals, and follow the official and professional chemical substance database.

Last Update：2024-04-09 15:18:00