837392-62-8 - Names and Identifiers
Name | 1-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole
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Synonyms | 1-Methyl-5-(4 AKOS BRN-1159 2-dioxaborolan-2-yl)-1H-indole 1-Methyl-5-indoleboronic acid pinacol ester 1-METHYLINDOLE-5-BORONIC ACID, PINACOL ESTER 1-Methyl-5-(4,4,5,5-tetramethyl-1,2,3-dioxaborolan-2-yl)-1H-indole 1-METHYL-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-1H-INDOLE 1-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole 1-Methyl-5-indoleboronic acid pinacol ester, 1-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole
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CAS | 837392-62-8
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EINECS | 1592732-453-0 |
InChI | InChI=1/C15H20BNO2/c1-14(2)15(3,4)19-16(18-14)12-6-7-13-11(10-12)8-9-17(13)5/h6-10H,1-5H3 |
837392-62-8 - Physico-chemical Properties
Molecular Formula | C15H20BNO2
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Molar Mass | 257.14 |
Density | 1.05±0.1 g/cm3(Predicted) |
Melting Point | 110-114 °C (lit.) |
Boling Point | 391.3±15.0 °C(Predicted) |
Flash Point | 190.466°C |
Vapor Presure | 0mmHg at 25°C |
Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
Refractive Index | 1.534 |
837392-62-8 - Risk and Safety
Hazard Symbols | Xi - Irritant
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Safety Description | S22 - Do not breathe dust.
S24/25 - Avoid contact with skin and eyes.
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WGK Germany | 3 |
Hazard Note | Irritant |
837392-62-8 - Introduction
1-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole is an organic compound with the chemical formula C15H19BO2N. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 1-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole is a colorless or light yellow solid.
-Melting point: Its melting point range is about 70-75°C.
-Solubility: Soluble in some organic solvents, such as chloroform, ethanol, etc.
Use:
- 1-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole is an important organic synthesis intermediate, commonly used in organic synthesis reactions.
-It can be used to construct a fused indole ring structure to synthesize biologically active compounds, such as drugs and pesticides.
Preparation Method:
1-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole can be prepared in many ways, one of which is commonly used:
-First, 1-methylindole is reacted with boronic acid diphenyl ester under alkaline conditions to obtain boronic acid methylindole ester.
-Then, the ester group in the boronic acid methyl indole ester is replaced with tetramethylborate (such as tetramethylborate) to obtain 1-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole.
Safety Information:
Last Update:2024-04-09 21:01:54