844891-04-9
1,3,5-Trimethyl-1H-pyrazole-4-boronic acid pinacol ester
CAS: 844891-04-9
Molecular Formula: C12H21BN2O2
844891-04-9 - Names and Identifiers
844891-04-9 - Physico-chemical Properties
| Molecular Formula | C12H21BN2O2 |
| Molar Mass | 236.12 |
| Density | 1.04±0.1 g/cm3(Predicted) |
| Melting Point | 91-93°C |
| Boling Point | 335.7±42.0 °C(Predicted) |
| Flash Point | 156.8°C |
| Vapor Presure | 0.000229mmHg at 25°C |
| pKa | 3.13±0.10(Predicted) |
| Storage Condition | Inert atmosphere,Store in freezer, under -20°C |
| Refractive Index | 1.503 |
844891-04-9 - Risk and Safety
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R22 - Harmful if swallowed |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S36 - Wear suitable protective clothing. S22 - Do not breathe dust. |
| WGK Germany | 3 |
| Hazard Note | Harmful |
844891-04-9 - Introduction
1,3, acid pinacol ester is an organic compound whose chemical formula is C12H21BN4O2. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: This is a white crystalline solid.
-Melting point: about 61-63 degrees Celsius.
-Solubility: The compound has good solubility in common organic solvents.
Use:
- 1,3, acid pinacol ester can be used as a raw material for reagents and catalysts in organic synthesis.
-It is an important reagent for the coupling reaction of C- C bonds and C- N bonds.
Preparation Method:
1,3, acid pinacol ester is mainly prepared by the following steps:
1. First, 1,3, 5-trimethyl-1H-pyrazole is reacted with concentrated sulfuric acid to generate 1,3, 5-trimethyl-1H-pyrazole-4-sulfate.
2. Then, 1,3, 5-trimethyl-1H-pyrazole-4-sulfate is reacted with ethyl triboronate to produce the target compound 1,3, acid pinacol ester.
3. Finally, the pure product can be obtained through crystal chemistry.
Safety Information:
1,3, acid: pinacol ester has better security, but the following matters still need to be paid attention:
-Avoid direct contact with skin and eyes during operation to prevent irritation and damage.
-Wear suitable personal protective equipment such as protective gloves, face shield and goggles when using.
-Keep sealed when stored, away from fire and flammable substances.
-Follow local chemical waste disposal regulations when disposing of waste.
-Before use or storage, you should understand and follow the relevant safety guidelines and procedures.
Nature:
-Appearance: This is a white crystalline solid.
-Melting point: about 61-63 degrees Celsius.
-Solubility: The compound has good solubility in common organic solvents.
Use:
- 1,3, acid pinacol ester can be used as a raw material for reagents and catalysts in organic synthesis.
-It is an important reagent for the coupling reaction of C- C bonds and C- N bonds.
Preparation Method:
1,3, acid pinacol ester is mainly prepared by the following steps:
1. First, 1,3, 5-trimethyl-1H-pyrazole is reacted with concentrated sulfuric acid to generate 1,3, 5-trimethyl-1H-pyrazole-4-sulfate.
2. Then, 1,3, 5-trimethyl-1H-pyrazole-4-sulfate is reacted with ethyl triboronate to produce the target compound 1,3, acid pinacol ester.
3. Finally, the pure product can be obtained through crystal chemistry.
Safety Information:
1,3, acid: pinacol ester has better security, but the following matters still need to be paid attention:
-Avoid direct contact with skin and eyes during operation to prevent irritation and damage.
-Wear suitable personal protective equipment such as protective gloves, face shield and goggles when using.
-Keep sealed when stored, away from fire and flammable substances.
-Follow local chemical waste disposal regulations when disposing of waste.
-Before use or storage, you should understand and follow the relevant safety guidelines and procedures.
Last Update：2024-04-10 22:29:15
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Spot supply
Product Name: 1,3,5-Trimethyl-1H-Pyrazole-4-Boronic Acid Pinacol Ester Visit Supplier Webpage Request for quotationCAS: 844891-04-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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