84639-84-9

84639-84-9 - Names and Identifiers

Name	7-hydroxy-1H-indole-2-carboxylic acid
Synonyms	7-Hydroxyindole-2-carboxylic acid 7-HYDROXYINDOLE-2-CARBOXYLIC ACID 7-hydroxy-1H-indole-2-carboxylic acid 7-Hydroxy-1H-indole-2-carboxylic acid 7-HYDROXY-1H-INDOLE-2-CARBOXYLIC ACID 1H-Indole-2-carboxylic acid, 7-hydroxy-
CAS	84639-84-9
InChI	InChI=1/C9H7NO3/c11-7-3-1-2-5-4-6(9(12)13)10-8(5)7/h1-4,10-11H,(H,12,13)

84639-84-9 - Physico-chemical Properties

Molecular Formula	C9H7NO3
Molar Mass	177.16
Density	1.570±0.06 g/cm3(Predicted)
Melting Point	252 °C
Boling Point	511.4±30.0 °C(Predicted)
Flash Point	263.1°C
Vapor Presure	2.79E-11mmHg at 25°C
pKa	4.37±0.30(Predicted)
Storage Condition	2-8°C
Refractive Index	1.78

84639-84-9 - Risk and Safety

Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.

84639-84-9 - Introduction

Acid is an organic compound with the chemical formula C9H7NO3. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: acid is a white to light yellow crystalline solid.
-Solubility: Soluble in hot water, ethanol, ether and chloroform, slightly soluble in cold water.
-Melting point: about 261-263 ℃.
- pH: In aqueous solution, its pH is about 5-7.

Use:
-Chemical research: acid is an important organic synthetic intermediate, which has a wide range of uses in the research of biochemistry and medicinal chemistry.
-Drug research and development: Due to its characteristics of natural indole alkaloids, it can be used to synthesize a variety of drugs, such as antibacterial drugs and anti-cancer drugs.

Preparation Method:
-The commonly used synthesis method is to react indole with bromoacetic acid to generate 7-bromoindole-2-carboxylic acid, and then to obtain acid by reduction and reaction.
-There are other synthetic methods such as direct selective oxidation in indole-2, 3-dione to prepare acid.

Safety Information:
-the toxicity study of acid is limited and there is no clear toxicity data. However, as a chemical, it is necessary to follow general safety practices.
-Wear appropriate personal protective equipment, such as lab gloves, goggles and lab coats, to avoid inhalation, swallowing or skin contact.
-Reduce conditions that may cause dust, mist or steam to be released during use or handling, and avoid sparks, open flames and heat sources.
-For more detailed safety information about acid, please refer to the specific safety data sheet.

Last Update：2024-04-09 02:00:48