849062-36-8

849062-36-8 - Names and Identifiers

Name	(3-bromo-5-methylphenyl)boronic acid
Synonyms	AKOS BRN-0928 3-BROMO-5-METHYLPHENYLBORONIC ACID 3-BROMO-5-METHYLBENZENEBORONIC ACID (3-bromo-5-methylphenyl)boronic acid Boronic acid,B-(3-broMo-5-Methylphenyl)-
CAS	849062-36-8
InChI	InChI=1/C7H8BBrO2/c1-5-2-6(8(10)11)4-7(9)3-5/h2-4,10-11H,1H3
InChIKey	KKEPYOBFWSGWLQ-UHFFFAOYSA-N

849062-36-8 - Physico-chemical Properties

Molecular Formula	C7H8BBrO2
Molar Mass	214.85
Density	1.57±0.1 g/cm3(Predicted)
Melting Point	278-283°C(lit.)
Boling Point	351.8±52.0 °C(Predicted)
Flash Point	166.566°C
Vapor Presure	0mmHg at 25°C
pKa	7.65±0.10(Predicted)
Storage Condition	Inert atmosphere,2-8°C
Refractive Index	1.585

849062-36-8 - Risk and Safety

Hazard Symbols	Xi - Irritant
Safety Description	S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes.
WGK Germany	3
Hazard Note	Irritant/Keep Cold

849062-36-8 - Introduction

(3-bromo-5-methylphenyl)boronic acid is an organic compound with the chemical formula C7H8BBrO2. Here are some information about its nature, use, formulation and safety:

Nature:
-Appearance: Colorless or light yellow solid.
-Melting point: about 140°C.
-Solubility: Soluble in organic solvents such as dichloromethane, ethanol and ether, slightly soluble in water.
-Stability: Stable at room temperature.

Use:
-Catalyst:(3-bromo-5-methylphenyl)boronic acid is widely used as a catalyst for organic synthesis reactions.
-Drug intermediates: It can also be used to prepare intermediates for drugs and other organic compounds.
-Research use: Because it is very valuable for the application of coordination chemistry, it is widely used in coordination chemistry and coordination polymer research.

Preparation Method:
(3-bromo-5-methylphenyl)boronic acid can be prepared by the following steps:
1. Add (3-bromo-5-methylphenyl)boronic acid benzyl ester (3-bromo-5-methyl benzeneboronic acid methyl ester) to the reaction solvent.
2. Add boric acid (boronic acid) or other boric acid reagents, such as triphenyl boric acid (triphenylboronic acid). The reaction produces (3-bromo-5-methylphenyl)boronic acid.

Safety Information:
- (3-bromo-5-methylphenyl)boronic acid has no obvious safety hazards under normal use conditions.
-but still need to pay attention to the traditional laboratory safety operation.
-Avoid contact with skin and eyes and use personal protective equipment if necessary.
-It should be operated in a well-ventilated place to avoid inhaling dust or gas.
-Wash your hands thoroughly before eating or smoking. After operation, waste is carefully disposed of and disposed of in compliance with relevant regulations.

Please note that the chemical properties and safety information is based on existing knowledge and research results, but specific applications and operations still need to be evaluated and controlled based on actual conditions. When using chemicals, follow proper laboratory practices and safe practices.

Last Update：2024-04-09 21:04:16