849924-49-8

849924-49-8 - Names and Identifiers

Name	(1R)-1-[BIS(4-METHOXY-3,5-DIMETHYLPHENYL)PHOSPHINO]-2-[(1R)-1-[BIS(2-METHYLPHENYL)PHOSPHINO]ETHYL]FERROCENE
Synonyms	r-3,5me-4meoph-2-meph (R)-1-{(S)-2-[BIS(4-METHOXY-3,5-DIMETHYLPHENYL)PHOSPHINO]FERROCENYL}-ETHYLBIS(2- (R)-1-[(S)-2-[Bis(4-methoxy-3,5-dimethylphenyl) phosphino]ferrocenyl]ethyldi-o-tolylphosphine (r)-1-{(s)-2-[bis(4-methoxy-3,5-dimethylphenyl)phosphino]ferrocenyl}-ethylbis(2-methylphenyl)phosphine (R)-1-{(SP)-2-[Bis(4-Methoxy-3,5-diMethylphenyl)phosphino]ferrocenyl}-ethylbis(2-Methylphenyl)phosphine (R)-1-[(S)-2-Di-(4-methoxy-3,5-dimethylphenyl-phosphino)ferrocenyl]-ethyl-di-(2-methylphenyl)-phosphine (1R)-1-[BIS(4-METHOXY-3,5-DIMETHYLPHENYL)PHOSPHINO]-2-[(1R)-1-[BIS(2-METHYLPHENYL)PHOSPHINO]ETHYL]FERROCENE
CAS	849924-49-8

849924-49-8 - Physico-chemical Properties

Molecular Formula	C39H43O2P2.C5H5.Fe
Molar Mass	726.654
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C

849924-49-8 - Risk and Safety

WGK Germany	3
HS Code	29319090

849924-49-8 - Introduction

(1R)-1-[BIS(4-METHOXY-3,5-DIMETHYLPHENYL)PHOSPHINO]-2-[(1R)-1-[BIS(2-METHYLPHENYL)PHOSPHINO]ETHYL]FERROCENE, (R)-Bis-MeO-DMP-Fc-P for short;

Properties: (R)-Bis-MeO-DMP-Fc-P is a chiral organometallic compound that appears as a yellow to orange crystalline solid. It has good thermal stability and solubility.

Purpose: (R)-Bis-MeO-DMP-Fc-P is an important chiral ligand, which is widely used in metal catalyzed reactions and metal organic chemistry. It can be used as a ligand of Lefer catalysts for asymmetric catalytic reactions, such as asymmetric hydrogenation, allylation, cyclization, disproportionation and cross-coupling reactions. It can also be used in asymmetric catalytic reduction, rearrangement and oxidation reactions in organic synthesis.

Production Method: The synthesis of (R)-Bis-MeO-DMP-Fc-P is usually carried out by a multi-step reaction. The most common method is to use ferrocene and chiral tertiary amine as starting materials, through the Suzuki coupling reaction under the catalysis of boronic acid to generate the target compound.

Safety Information: (R)-Bis-MeO-DMP-Fc-P Toxicity and Hazard Information No detailed studies have been reported, but general organometallic compounds need to be handled with good laboratory practices and personal protective measures to avoid direct contact with skin and inhalation. When using and handling, it is necessary to refer to the relevant chemical safety technical guidelines, and take corresponding measures according to the specific situation.

Last Update：2024-04-09 02:00:49