85003-78-7

85003-78-7 - Names and Identifiers

Name	Phenol, 2-(5-amino-1,3,4-thiadiazol-2-yl)-
Synonyms	Phenol, 2-(5-aMino-1,3,4-thiadiazol-2-yl)- Phenol, 2-(5-amino-1,3,4-thiadiazol-2-yl)-
CAS	85003-78-7

85003-78-7 - Physico-chemical Properties

Molecular Formula	C8H7N3OS
Molar Mass	193.23
Density	1.471±0.06 g/cm3(Predicted)
Melting Point	229-230 °C
Boling Point	413.6±47.0 °C(Predicted)
pKa	7.97±0.30(Predicted)

85003-78-7 - Introduction

Phenol, 2-(5-amino-1,3,4-thiadiazol-2-yl)-, also known as o-hydroxyphenyl-p-aminothiazine, has the chemical formula C7H7N3OS. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: Phenol, 2-(5-amino-1,3,4-thiadiazol-2-yl)-is a white crystalline solid.
-Solubility: It has low solubility in water, but higher solubility in organic solvents such as alcohols, ethers and ketones.
-Stability: The compound is relatively stable at room temperature and can be stored for a long time under dark and dry conditions.
- pH: Its solution in water is weakly acidic.

Use:
-Drug: Phenol, 2-(5-amino-1,3,4-thiadiazol-2-yl)-is an important intermediate compound that can be used to synthesize various biologically active drugs.
-Dye: It can also be used as a precursor of organic dyes for the dye industry.
-Photosensitizer: The compound can also be used as a photosensitizer, applied to photosensitive materials and photosensitive devices.

Preparation Method:
A common method for preparing Phenol, 2-(5-amino-1,3,4-thiadiazol-2-yl)-is through the substitution reaction of nitrobenzene. The specific steps include the reaction of nitrobenzene with sodium sulfoxylate and thiourea to form 1-nitro-aniline, which is then reacted with sodium thiocyanate to obtain 5-thiocyano-2-aminoaniline. Finally, by reaction with sulfuric acid, Phenol, 2-(5-amino-1,3,4-thiadiazol-2-yl)-is produced-.

Safety Information:
-For the use and handling of chemicals, the appropriate safety procedures should be followed.
- Phenol, 2-(5-amino-1,3,4-thiadiazol-2-yl)-is relatively stable under normal conditions, but it is still necessary to avoid exposure to high temperatures and fire sources.
-When preparing and handling the compound, care should be taken to use appropriate personal protective equipment, such as safety glasses and protective gloves.
-This compound may be potentially harmful to the environment. Waste liquids and waste materials should be properly disposed of and environmental protection regulations should be followed.

In addition, if the compound needs to be used, it is recommended to operate under the guidance of professionals and follow relevant regulations and regulations.

Last Update：2024-04-09 21:00:56