85216-55-3

85216-55-3 - Names and Identifiers

Name	3-Amino-5-bromo-6-methyl-2(1H)-pyridinone
Synonyms	3-AMINO-5-BROMO-6-METHYLPYRIDIN-2-OL 3-Amino-5-bromo-6-methyl-1H-pyridin-2-one 3-Amino-5-bromo-6-methylpyridin-2(1H)-one 3-Amino-5-bromo-6-methyl-2(1H)-pyridinone 3-AMino-5-broMo-6-Methyl-2(1H)-pyridinone 2-Hydroxy-3-amino-5-bromo-6-methylpyridine 2(1H)-Pyridinone, 3-amino-5-bromo-6-methyl-
CAS	85216-55-3
InChI	InChI=1S/C6H7BrN2O/c1-3-4(7)2-5(8)6(10)9-3/h2H,8H2,1H3,(H,9,10)

85216-55-3 - Physico-chemical Properties

Molecular Formula	C6H7BrN2O
Molar Mass	203.04
Storage Condition	Keep in dark place,Inert atmosphere,Room temperature

85216-55-3 - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	R22 - Harmful if swallowed R37/38 - Irritating to respiratory system and skin. R41 - Risk of serious damage to eyes
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39 - Wear eye / face protection.

85216-55-3 - Introduction

3-Amino-5-bromo-6-methyl-2(1H)-pyridinone is an organic compound whose chemical formula is C6H6BrN3O. The following is a detailed description of its nature, use, preparation and safety information:

Nature:
-Appearance: 3-Amino-5-bromo-6-methyl-2(1H)-pyridinone is a colorless to light yellow solid.
-Solubility: It has low solubility in water and is soluble in organic solvents such as ethanol and dichloromethane.
-Melting point: Its melting point is 100-105 degrees Celsius.

Use:
-Chemical synthesis: 3-Amino-5-bromo-6-methyl-2(1H)-pyridinone is often used as an intermediate in organic synthesis. It can be used to synthesize other organic compounds, such as drugs, pesticides, etc.
-Drug research: Due to some of its characteristics in vivo, 3-Amino-5-bromo-6-methyl-2(1H)-pyridinone is used in drug research, especially in the field of anti-tumor drug development.

Preparation Method:
The preparation method of 3-Amino-5-bromo-6-methyl-2(1H)-pyridinone can be carried out by the following steps:
1. The reaction of dimethyl malonate and dimethyl malonate with ferric tribromide produces 4-bromo-6-methylpyridine-2, 3-dione under appropriate conditions.
2. The compound obtained in step 1 is reacted with ammonia gas to obtain 3-amino-5-bromo-6-methylpyridin-2 (1H)-one.
3. The compound obtained in step 2 is reacted with sodium hydroxide to produce 3-Amino-5-bromo-6-methyl-2(1H)-pyridinone.

Safety Information:
-3-Amino-5-bromo-6-methylpyridine is subject to general laboratory safety regulations during handling and storage.
-It is an organic compound with certain toxicity. Direct contact or inhalation may be harmful to human health.
-When using, you should wear protective glasses and gloves, and ensure that you operate in a well-ventilated environment.
-Try to avoid its contact with strong oxidants, strong acids and strong bases to avoid dangerous reactions.
-Disposal of waste in accordance with local regulations.

Last Update：2024-04-09 02:00:48