853-23-6
dehydroisoandrosterone 3-acetate
CAS: 853-23-6;1239-31-2
Molecular Formula: C21H30O3
853-23-6 - Names and Identifiers
853-23-6 - Physico-chemical Properties
| Molecular Formula | C21H30O3 |
| Molar Mass | 330.47 |
| Density | 1.0998 (rough estimate) |
| Melting Point | 168-170°C(lit.) |
| Boling Point | 407.89°C (rough estimate) |
| Flash Point | 188.1°C |
| Water Solubility | 11.5mg/L(temperature not stated) |
| Vapor Presure | 0Pa at 20℃ |
| Storage Condition | Refrigerator |
| Refractive Index | 1.5192 (estimate) |
| Use | For the synthesis of steroid hormone drugs |
| In vivo study | Dehydroisoandrosterone implants increases aggression in a laboratory-based simulated territorial intrusion. Brains of Dehydroisoandrosterone-implanted birds show higher aromatase mRNA expression in the preoptic area (POA) and higher androgen receptor mRNA expression in the periventricular nucleus of the medial striatum (pvMSt) and ventromedial nucleus of the hypothalamus (VMH). The Dehydroisoandrosterone-induced increases in aromatase expression in the POA and androgen receptor expression in the pvMSt are consistent with previously reported seasonal increases in these markers associated with naturally elevated Dehydroisoandrosterone levels. Dehydroisoandrosterone supplementation (10.2 mg/kg) alone significantly increases mice body weight (BW), muscle weight, testosterone level, and glycogen contents (liver and muscle) when compared with SC group. |
853-23-6 - Risk and Safety
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| RTECS | BV8396810 |
853-23-6 - Reference Information
| LogP | 5.1 at 20℃ |
| biological activity | dehydroepiandroster3-acetate is a precursor of male/female hormones, able to modulate aggressive behavior in vertebrates. |
| purpose | for the synthesis of steroid hormone drugs dehydroepiandrosterone acetate is a synthetic hormone, important intermediates of steroid hormone drugs such as family planning supplies, which can synthesize testosterone, methyl testosterone, estradiol, estriol |
Last Update：2024-04-09 15:16:53
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