85684-64-6

85684-64-6 - Names and Identifiers

Name	2-(difluoromethoxy)benzyl bromide
Synonyms	O-DIFLUOROMETHOXYBENZYLBROMIDE à-bromo-2-difluoromethoxytoluene 2-(DIFLUOROMETHOXY)BENZYL BROMIDE 2-(difluoromethoxy)benzyl bromide alpha-Bromo-2-difluoromethoxytoluene 1-(BroMoMethyl)-2-(difluoroMethoxy)benzene 1-(bromomethyl)-2-(difluoromethoxy)benzene 1-(Bromomethyl)-2-(difluoromethoxy)benzene, 2-(Bromomethyl)phenyl difluoromethyl ether
CAS	85684-64-6
InChI	InChI=1/C8H7BrF2O/c9-5-6-3-1-2-4-7(6)12-8(10)11/h1-4,8H,5H2

85684-64-6 - Physico-chemical Properties

Molecular Formula	C8H7BrF2O
Molar Mass	237.04
Density	1,555 g/cm3
Boling Point	222°C
Flash Point	108°C
Water Solubility	Immiscible with water.
Vapor Presure	0.131mmHg at 25°C
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Sensitive	Lachrymatory
Refractive Index	1.518
MDL	MFCD00190103

85684-64-6 - Risk and Safety

Hazard Symbols	C - Corrosive
Risk Codes	R34 - Causes burns R36/37/38 - Irritating to eyes, respiratory system and skin. R40 - Limited evidence of a carcinogenic effect
Safety Description	S24/25 - Avoid contact with skin and eyes. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
UN IDs	2922
Hazard Note	Corrosive/Lachrymatory
Hazard Class	8
Packing Group	III

85684-64-6 - Introduction

2-(difluoromethoxy)benzyl bromide is an organic compound with the chemical formula C8H7BrF2O. It is a colorless to yellowish liquid with a special pungent odor at room temperature.

2-(difluoromethoxy)benzyl bromide is often used as an important intermediate in organic synthesis. It can be used in the field of medicine for the synthesis of drugs, such as anti-cancer drugs, antipsychotic drugs, anti-allergic drugs. In addition, it can also be used to synthesize pesticides, dyes and medical materials.

There are many methods for preparing 2-(difluoromethoxy)benzyl bromide. The common method is to react benzyl bromide with difluormethanol. The reaction is carried out under an acidic condition and is promoted by adding an ether solvent and a dilute sulfuric acid catalyst.

Regarding the safety information of 2-(difluoromethoxy)benzyl bromide, it is an irritant substance that may irritate the skin, eyes and respiratory system. Therefore, contact with skin and eyes should be avoided during operation, and good ventilation conditions should be ensured. At the same time, care must be taken to properly store and handle the compound to avoid contact with ignition sources or oxidizing agents.

Last Update：2024-04-09 21:54:55