85870-47-9

85870-47-9 - Names and Identifiers

Name	3-Quinolinecarboxylic acid, 1,2-dihydro-2-oxo-, ethyl ester
Synonyms	Ethyl 2-oxo-1,2-dihydro-q... ethyl 2-oxo-1H-quinoline-3-carboxylate ethyl 2-oxo-1,2-dihydroquinoline-3-carboxylate Ethyl 2-oxo-1,2-dihydro-quinoline-3-carboxylate 2-Oxo-1,2-dihydro-quinoline-3-carboxylic acid ethyl ester 3-Quinolinecarboxylic acid, 1,2-dihydro-2-oxo-, ethyl ester
CAS	85870-47-9

85870-47-9 - Physico-chemical Properties

Molecular Formula	C12H11NO3
Molar Mass	217.22
Density	1.246±0.06 g/cm3(Predicted)
Melting Point	163-164 °C(Solv: ethanol (64-17-5))
Boling Point	421.0±45.0 °C(Predicted)
pKa	10.71±0.70(Predicted)
Storage Condition	2-8°C

85870-47-9 - Introduction

3-Quinolinecarboxylic acid, 1,2-dihydro-2-oxo-, ethyl ester is an organic compound with the chemical formula C12H11NO3. It is a solid and has the following properties:

1. Appearance: 3-Quinolinecarboxylic acid, 1,2-dihydro-2-oxo-, ethyl ester is a colorless to pale yellow crystal or crystalline powder.

2. Solubility: It is soluble in common organic solvents such as chloroform, ethanol and ether, while its solubility in water is low.

3. chemical reaction: 3-quinolinecarboxylic acid, 1,2-dihydro-2-oxo-, ethyl ester can undergo ester hydrolysis reaction to generate corresponding acid and alcohol. It can be prepared by reaction of an esterifying agent and a carboxylic acid.

The main uses of this compound are as follows:

1. Drug intermediate: 3-Quinolinecarboxylic acid, 1,2-dihydro-2-oxo-, ethyl ester can be used as an intermediate for the synthesis of drugs. As an inhibitor, it has the potential to inhibit the biosynthesis of DNA and RNA.

2. pesticide: it can also be used to synthesize some pesticides, such as insecticides, fungicides, etc.

3. Antibacterial agent: This compound can be used as an antibacterial agent, has antibacterial activity, and can be used to prevent and treat bacterial infections such as pneumococcus.

In the preparation of the compound, an ester can be formed by reacting 2-carbonyl -1, 2-dihydro-3-quinolinecarboxylic acid with ethanol, using an esterifying agent such as hydrochloric acid or sulfuric acid, and dehydrating reaction.

Regarding safety information, this compound has certain toxicity, so it is necessary to strictly follow relevant safety practices when using and storing. In a laboratory environment, it is recommended to wear appropriate personal protective equipment such as lab gloves, goggles, and lab coats. Avoid inhaling dust or vapors of the compound and avoid direct skin contact. In case of accidental contact, rinse immediately with plenty of water and seek medical help. In addition, the compound must be stored and disposed of properly to avoid contamination of the environment.

Last Update：2024-04-09 20:52:54