859164-45-7

859164-45-7 - Names and Identifiers

Name	4-(2-fluorophenyl)tetrahydro-2H-pyran-4-carbonitrile
Synonyms	4-(2-fluorophenyl)oxane-4-carbonitrile 4-(2-fluorophenyl)tetrahydro-2H-pyran-4-carbonitrile
CAS	859164-45-7

859164-45-7 - Physico-chemical Properties

Molecular Formula	C12H12FNO
Molar Mass	205.2281832
Storage Condition	Room Temprature

859164-45-7 - Introduction

4-(2-fluorophenyl)tetrahydro-2H-pyran-4-carbonitrile is an organic compound with the chemical formula C14H13FN and a molecular weight of 217.26g/mol.

Nature:
-Appearance: Colorless to light yellow crystalline solid
-Solubility: Soluble in organic solvents such as ethanol, dimethyl sulfoxide, slightly soluble in water
-Melting point: 72-74 ° C
-Stability: The compound is relatively stable under dry conditions, but it will decompose under the influence of light and high temperature

Use:
-Intermediate: It is often used as an intermediate for the synthesis of other organic compounds, such as heterocyclic compounds and functional compounds.
-Drug research: Due to its unique structure and chemical properties, 4-(2-fluorophenyl)tetrahydro-2H-pyran-4-carbonitrile has important application value in the field of drug research.

Method:
4-(2-fluorophenyl)tetrahydro-2H-pyran-4-carbonitrile can be synthesized by the following steps:
1. 2-fluoroacetophenone was reacted with sodium cyanide under alkaline conditions to form 2-fluoroacetophenone cyanide;
2. 2-Fluoroacetophenone cyanide is condensed with 1,3-propanediol under acidic conditions to form 4-(2-fluorophenyl)tetrahydro-2H-pyran-4-carbonitrile.

Safety Information:
Specific toxicity and safety data regarding 4-(2-fluorophenyl)tetrahydro-2H-pyran-4-carbonitrile are currently unknown. When using this compound, it is necessary to strictly abide by the laboratory's safe operation regulations and wear appropriate protective equipment to ensure personal safety.

Last Update：2024-04-09 21:54:55