863239-60-5
Glyco Obeticholic acid
CAS: 863239-60-5
Molecular Formula: C28H47NO5
863239-60-5 - Names and Identifiers
| Name | Glyco Obeticholic acid |
| Synonyms | Glyco Obeticholic acid Glyco-obeticholic acid D4 Glycine Obeticholic acid D5 Glycine, N-[(3α,5β,6α,7α)-6-ethyl-3,7-dihydroxy-24-oxocholan-24-yl]- |
| CAS | 863239-60-5 |
863239-60-5 - Physico-chemical Properties
| Molecular Formula | C28H47NO5 |
| Molar Mass | 477.69 |
| Density | 1.125±0.06 g/cm3(Predicted) |
| Boling Point | 666.4±40.0 °C(Predicted) |
| pKa | 3.58±0.10(Predicted) |
| In vitro study | Obeticholic acid is conjugated with glycine in the liver to form glycol-obeticholic acid, which is secreted into bile. Microorganisms in the ileum and colon can deconjugate glyco-obeticholic acid, converting it into the parent drug, which may then be reabsorbed or excreted in faeces. |
863239-60-5 - References
| biological activity | Glyco-obeticholic acid is the active metabolite of taurine. Obeticholic Acid is an oral bioavailable farnicoid X receptor (FXR) agonist. |
Last Update：2024-04-09 22:09:11
