863753-35-9

863753-35-9 - Names and Identifiers

Name	{2-[(tert-butoxycarbonyl)amino]pyridin-3-yl}boronic acid
Synonyms	2-(Boc-amino)pyridine-3-boronic Acid 2-(N-Boc-amino)pyridine-3-boronic acid 2-(t-Butoxycarbonylamino)pyridine-3-boronic acid 2-(tert-Butoxycarbonylamino)pyridine-3-boronicacid 2-(tert-Butoxycarbonylamino)pyridine-3-boronic acid {2-[(tert-butoxycarbonyl)amino]pyridin-3-yl}boronic acid (2-[(TERT-BUTOXYCARBONYL)AMINO]PYRIDIN-3-YL)BORONIC ACID (2-[(Tert-Butoxycarbonyl)Amino]Pyridin-3-Yl)Boronic Acid [2-[(2-methylpropan-2-yl)oxycarbonylamino]pyridin-3-yl]boronic acid Carbamic acid, N-(3-borono-2-pyridinyl)-, C-(1,1-dimethylethyl) ester [2-[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]-3-pyridinyl]boronic acid
CAS	863753-35-9
InChI	InChI=1/C10H15BN2O4/c1-10(2,3)17-9(14)13-8-7(11(15)16)5-4-6-12-8/h4-6,15-16H,1-3H3,(H,12,13,14)

863753-35-9 - Physico-chemical Properties

Molecular Formula	C10H15BN2O4
Molar Mass	238.05
Density	1.23±0.1 g/cm3(Predicted)
pKa	6.90±0.53(Predicted)
Storage Condition	Inert atmosphere,Store in freezer, under -20°C
Refractive Index	1.531

863753-35-9 - Introduction

{2-[(tert-butoxycarbonyl)amino]pyridin-3-yl}boronic acid is an organic compound with the chemical formula C12H17BN2O4.

Its properties are as follows:
-Appearance: White crystalline powder.
-Melting point: about 211-214°C.
-Solubility: Soluble in some organic solvents, such as methanol, dimethyl sulfoxide, chloroform, etc.

{2-[(tert-butoxycarbonyl)amino]pyridin-3-yl}boronic acid has a wide range of applications:
-As an important intermediate in organic synthesis, it is used to synthesize various nitrogen-containing organic compounds.
-can be used to synthesize drugs, pesticides and other active molecules.
-In coordination chemistry, it can be used as a ligand to participate in the preparation and reaction of metal organic compounds.

Preparation Method:
{2-[(tert-butoxycarbonyl)amino]pyridin-3-yl}boronic acid can be synthesized by the following steps:
1. 2-Chloropyridine is reacted with N-tert-butoxycarbonylaminosilane to obtain 2-(tert-butoxycarbonylamino) pyridine.
2. React 2-(tert-butoxycarbonylamino) pyridine with triphenylboron to obtain the final product {2-[(tert-butoxycarbonyl)amino]pyridin-3-yl}boronic acid.

Safety Information:
- {2-[(tert-butoxycarbonyl)amino]pyridin-3-yl}boronic acid may be irritating to skin, eyes and respiratory system. Wear protective equipment to avoid contact.
-Avoid inhaling dust and vapor from the solution, and ensure that it is operated in a well-ventilated place.
-Storage should be sealed to avoid contact with oxidants and acidic substances.

Last Update：2024-04-09 02:00:48