Molecular Formula | C22H17Cl2F6N3O3 |
Molar Mass | 556.2851 |
Density | 1.51±0.1 g/cm3(Predicted) |
Solubility | DMSO: ≥ 221 mg/mL |
pKa | 12.50±0.46(Predicted) |
Storage Condition | -20℃ |
Physical and Chemical Properties | Bioactive Fluralaner (A1443, AH252723) is an oral systemic insecticide and acaricide. Fluralaner inhibits γ-aminobutyric acid (GABA)-gated chloride channels (GABAA receptors) and L-glutamate-gated chloride channels (GluCls). |
Use | The application of florerana mainly plays a role by interfering with GABA-gated chloride ion channels, which is similar to the targets of pesticides such as cyclopentadienes, phenylpyrazoles and macrolides. Flurerana is a broad-spectrum insecticide, which has good insecticidal activity against pests such as ticks, fleas, lice, hemiptera and diptera, and its virulence is higher than or comparable to commonly used insecticides. Florerana not only has no significant cross-resistance with existing insecticides, but also has good insecticidal activity against some resistant pests. |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 1.798 ml | 8.988 ml | 17.976 ml |
5 mM | 0.36 ml | 1.798 ml | 3.595 ml |
10 mM | 0.18 ml | 0.899 ml | 1.798 ml |
5 mM | 0.036 ml | 0.18 ml | 0.36 ml |
Nature:
1. It is a white to light yellow solid powder that is insoluble in water but soluble in organic solvents such as dimethyl sulfoxide.
2. It is an insecticide with efficient killing effects on fleas and ticks.
Usage:
Fluraliner is mainly used to prevent fleas and ticks on dogs and cats, effectively controlling parasites on pets and protecting them from parasitic infections.
Method:
The preparation method of Fluraliner is mainly obtained through chemical synthesis, and the specific synthesis route involves a series of organic synthesis steps, including different reactions and purification processes.
Security information:
1. When using, it is necessary to follow the prescribed dosage to avoid misuse or overuse.
2. In some cases, side effects may occur, such as decreased appetite, vomiting, diarrhea, etc.
3. When using Flurana, carefully read the instructions and follow the advice of a doctor or veterinarian.
the successful research and development of florerana has created a new research direction of GABA-gated chloride ion channel interfering agent, which has attracted the attention and favor of animal medicine and pesticide scientists.