869384-82-7

869384-82-7 - Names and Identifiers

Name	14-Deoxy-17-hydroxyandrographolide
Synonyms	14-DEOXY-17-HYDROXYANDROGRAPHOLI 14-Deoxy-17-hydroxyandrographolide 2(5H)-Furanone, 3-[2-[(1R,2S,4aS,5R,6R,8aS)-decahydro-6-hydroxy-2,5-bis(hydroxymethyl)-5,8a-dimethyl-1-naphthalenyl]ethyl]-
CAS	869384-82-7

869384-82-7 - Physico-chemical Properties

Molecular Formula	C20H32O5
Molar Mass	352.47
Density	1.148±0.06 g/cm3(Predicted)
Boling Point	552.1±20.0 °C(Predicted)
Specific Rotation(α)	?9.4 (c, 0.8 in MeOH)
pKa	14.99±0.10(Predicted)
Storage Condition	2-8℃

869384-82-7 - Introduction

14-deoxy -17-hydroxy Sophora cyanine (Ben) is a natural product obtained from Sophora plants. It belongs to the derivative of hydroxyl Sophora cyanine (andrographolide), and the oxygen atom on the 14-position is removed in the structure.

Properties: 14-deoxy -17-hydroxy Sophora cyanine is a white crystalline solid. Its chemical formula is C20H28O4 and its molecular weight is 332.44g/mol. It has a melting point of about 176-178 ° C.

Use: 14-deoxy-17-hydroxy Sophora cyanine has anti-inflammatory, antioxidant, anti-tumor and immunomodulatory pharmacological activities. Therefore, it has certain application potential in the field of traditional Chinese medicine, health care products and medicine. Studies have also shown that it has anti-inflammatory effects and can be used to treat inflammation-related diseases.

preparation method: 14-deoxy-17-hydroxysophora cyanine is generally obtained by extracting and purifying from Sophora plant (such as Sophora japonica (Andrographis paniculata)). Extraction methods include ultrasonic-assisted extraction, solvent extraction, etc.

Safety information: At present, the safety research of 14-deoxy-17-hydroxysophora cyanine is limited, so its toxicity and side effects are not clear. When used, further research and evaluation are needed to ensure its safety and effectiveness. During use, the correct dosage and use guidelines should be followed to reduce potential risks. In addition, individual reactions to the substance may vary, so it is best to consult a doctor or professional for advice before use.

Last Update：2024-04-09 20:49:11