Name | MK-2048 |
Synonyms | CS-1529 MK-2048 |
CAS | 869901-69-9 |
Molecular Formula | C21H21ClFN5O4 |
Molar Mass | 461.87 |
Density | 1.55 |
Storage Condition | -20℃ |
In vitro study | MK-2048 in Mg in vitro, the sensitivity of Q148K and N155H Viruses selectively resistant to Raltegravir to integrase strand transfer inhibitors, including MK-2048, was not altered. Recent studies have shown that MK-2048 act on peripheral blood monocytes and macrophages (PBMC) and C8166 Lymphocyte T cells with similar levels of anti-HIV activity. The EC50 was 0.4 nM, 0.9 nM and 11.5 nM, respectively. |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 2.165 ml | 10.826 ml | 21.651 ml |
5 mM | 0.433 ml | 2.165 ml | 4.33 ml |
10 mM | 0.217 ml | 1.083 ml | 2.165 ml |
5 mM | 0.043 ml | 0.217 ml | 0.433 ml |