870089-49-9

870089-49-9 - Names and Identifiers

Name	1-Boc-3-acetyl-azetidine
Synonyms	1-Boc-3-acetyl-azetidine TERT-BUTYL 3-ACETYLAZETIDINE-1-CARBOXYLATE 1-Azetidinecarboxylic acid, 3-acetyl-, 1,1-dimethylethyl ester
CAS	870089-49-9

870089-49-9 - Physico-chemical Properties

Molecular Formula	C10H17NO3
Molar Mass	199.25
Density	1.104±0.06 g/cm3(Predicted)
Boling Point	274.7±33.0 °C(Predicted)
pKa	-2.86±0.40(Predicted)
Storage Condition	2-8°C

870089-49-9 - Introduction

1-Boc-3-acetyl-azetidine is an organic compound with the following properties:

1. Appearance: Colorless to light yellow liquid or solid.
2. molecular formula: C13H21NO3.
3. Molecular weight: 239.31g/mol.
4. melting point: about 52-55 ℃.
5. Boiling point: about 265-267 ℃.
6. solubility: can be dissolved in common organic solvents, such as methanol, ethanol or dimethyl thiourea.
7. Stability: Stable under normal storage conditions.

1-Boc-3-acetyl-azetidine, as an intermediate compound, is widely used in organic synthesis and drug development. Its main uses include:

1. Chemical synthesis: As a structural unit of nitrogen-containing heterocycles, it can be used to construct complex organic molecules.
2. drug development: can be used for the synthesis of anti-tumor drugs, antiviral drugs, antibacterial drugs.
3. biological science research: can be applied to protein engineering, fluorescent dye synthesis and other fields.

The preparation of 1-Boc-3-acetyl-azetidine generally uses the following method:

The N-acetyl compound was obtained by reacting 1-azetidine with acetyl chloride under basic conditions. Then, 1-Boc-3-acetyl-azetidine is obtained by reacting the N-acetyl compound with Boc-Cl (tert-butoxycarbonyl chloride) under alkaline conditions.

For safety information, note the following when using 1-Boc-3-acetyl-azetidine:

1. Avoid direct contact with skin and eyes. If contact occurs, rinse immediately with plenty of water.
2. Wear appropriate personal protective equipment such as lab gloves, goggles and lab coats when using.
3. in use and storage to maintain good ventilation, avoid inhalation of aerosols.
4. avoid contact with strong oxidants or strong acids to prevent dangerous reactions.
5. Keep the container sealed during storage and store in a dry, cool place, away from fire and ignition sources.

When using 1-Boc-3-acetyl-azetidine, please follow strict laboratory safety practices and comply with relevant laws and regulations.

Last Update：2024-04-09 21:21:28