870481-87-1
Boc-7-Chloro-DL-tryptophan
CAS: 870481-87-1
Molecular Formula: C16H19ClN2O4
870481-87-1 - Names and Identifiers
870481-87-1 - Physico-chemical Properties
| Molecular Formula | C16H19ClN2O4 |
| Molar Mass | 338.79 |
870481-87-1 - Introduction
Boc-7-Chloro-DL-tryptophan is an organic compound whose chemical formula is C14H16ClN3O2. The following is an introduction to its nature, use, preparation and safety information:
Nature:
Boc-7-Chloro-DL-tryptophan is a white crystalline solid. It is soluble in some organic solvents such as dimethylformamide (DMF) and dichloromethane. It has a structure with the amino acid DL-tryptophan, but a heptachloro group is introduced on the amido protecting group.
Use:
Boc-7-Chloro-DL-tryptophan is an important intermediate in organic synthesis. It is commonly used in polypeptide synthesis and can introduce chloro groups to change the properties of polypeptide molecules. In addition, it has potential applications in studying the metabolism and mechanism of action of DL-tryptophan in vivo.
Preparation Method:
Boc-7-Chloro-DL-tryptophan can be prepared by introducing a protecting group into DL-tryptophan, followed by chloroalkylation. A common method of preparation is to react DL-tryptophan with a BOC-N-hydroxysuccinimide ester to form a protecting group, which is then reacted with phosphorus heptachloride to form Boc-7-Chloro-DL-tryptophan.
Safety Information:
The use and handling of Boc-7-Chloro-DL-tryptophan must follow general chemical safety practices. It may be irritating and corrosive to the eyes, skin and respiratory tract, so care should be taken to avoid direct contact with it. During the operation, personal protective equipment such as protective glasses, gloves and protective masks should be worn. During storage, it should be kept in a dry, cool place, away from fire and oxidizing agents.
Nature:
Boc-7-Chloro-DL-tryptophan is a white crystalline solid. It is soluble in some organic solvents such as dimethylformamide (DMF) and dichloromethane. It has a structure with the amino acid DL-tryptophan, but a heptachloro group is introduced on the amido protecting group.
Use:
Boc-7-Chloro-DL-tryptophan is an important intermediate in organic synthesis. It is commonly used in polypeptide synthesis and can introduce chloro groups to change the properties of polypeptide molecules. In addition, it has potential applications in studying the metabolism and mechanism of action of DL-tryptophan in vivo.
Preparation Method:
Boc-7-Chloro-DL-tryptophan can be prepared by introducing a protecting group into DL-tryptophan, followed by chloroalkylation. A common method of preparation is to react DL-tryptophan with a BOC-N-hydroxysuccinimide ester to form a protecting group, which is then reacted with phosphorus heptachloride to form Boc-7-Chloro-DL-tryptophan.
Safety Information:
The use and handling of Boc-7-Chloro-DL-tryptophan must follow general chemical safety practices. It may be irritating and corrosive to the eyes, skin and respiratory tract, so care should be taken to avoid direct contact with it. During the operation, personal protective equipment such as protective glasses, gloves and protective masks should be worn. During storage, it should be kept in a dry, cool place, away from fire and oxidizing agents.
Last Update：2024-04-10 22:29:15
