87164-90-7
ICI 153110
CAS: 87164-90-7
Molecular Formula: C11H11N3O
87164-90-7 - Names and Identifiers
| Name | ICI 153110 |
| Synonyms | ICI 153110 4,5-Dihydro-6-[(E)-2-(4-pyridinyl)ethenyl]-2H-pyridazin-3-one 3(2H)-Pyridazinone, 4,5-dihydro-6-[(1E)-2-(4-pyridinyl)ethenyl]- |
| CAS | 87164-90-7 |
87164-90-7 - Physico-chemical Properties
| Molecular Formula | C11H11N3O |
| Molar Mass | 201.22 |
| Storage Condition | 2-8℃ |
| Use | ICI 153110 is an orally effective phosphodiesterase inhibitor with vasodilating and contractile properties and is useful in the treatment of congestive heart failure. |
| In vivo study | ICI 153110 is an orally active phosphodiesterase inhibitor with both vasodilating and inotropic properties which is designed for the treatment of congestive cardiac failure. Fourteen animals have died as a direct or indirect consequence of ICI 153110 administration in the high-dose main test and reversibility groups. In the female rat dosed at 10 mg/kg/day ICI 153110 a mild focal arteritis is characterized by a predominantly and diffusely adventitial infiltration of mixed cells and early formation of fibrous tissue. The two rats dosed at 250 mg/kg/day ICI 153110 die prematurely from intratracheal intubation of dosing solution. Arteries from two further animals (dosed at 5 and 250 mg/kg/day ICI 153110) show minimal focal arteritis with medial necrosis, and medial and adventitial inflammation. |
87164-90-7 - Introduction
ICI 153110, whose chemical name is 3-(2,3-dimethylphenyl)-1-propenol, is an organic compound. The following is a description of the nature, use, preparation and safety information of ICI 153110:
Properties: ICI 153110 is a solid substance with a colorless or light yellow crystalline appearance. It has a relative molecular weight of about 232.31g/mol, a melting point of about 73 degrees Celsius, and a boiling point of about 324 degrees Celsius. The compound is soluble in organic solvents such as alcohols, ethers and acetates.
Uses: ICI 153110 is often used as a photoinitiator, especially in UV-sensitive polymer systems. It can initiate polymerization reaction by absorbing ultraviolet light and converting it into chemical energy, so as to realize the preparation of light curing or photosensitive polymer. In addition, ICI 153110 can also be used in photochemical processing, printing industry and two-dimensional code printing and other fields.
preparation method: the preparation method of ICI 153110 is generally realized by chemical synthesis. Specifically, ICI 153110 can be synthesized by subjecting reactants such as 2,3-dimethylphenylethylene and potassium hydroxide to a keto-alcohol interconversion reaction under appropriate conditions.
Security Information: ICI 153110 security is better. Care should be taken to avoid inhalation, swallowing or contact with skin and eyes. If contact occurs, wash with water immediately and seek medical help. During storage and handling, it should be separated from flammable materials and oxidizing agents, and kept sealed.
Properties: ICI 153110 is a solid substance with a colorless or light yellow crystalline appearance. It has a relative molecular weight of about 232.31g/mol, a melting point of about 73 degrees Celsius, and a boiling point of about 324 degrees Celsius. The compound is soluble in organic solvents such as alcohols, ethers and acetates.
Uses: ICI 153110 is often used as a photoinitiator, especially in UV-sensitive polymer systems. It can initiate polymerization reaction by absorbing ultraviolet light and converting it into chemical energy, so as to realize the preparation of light curing or photosensitive polymer. In addition, ICI 153110 can also be used in photochemical processing, printing industry and two-dimensional code printing and other fields.
preparation method: the preparation method of ICI 153110 is generally realized by chemical synthesis. Specifically, ICI 153110 can be synthesized by subjecting reactants such as 2,3-dimethylphenylethylene and potassium hydroxide to a keto-alcohol interconversion reaction under appropriate conditions.
Security Information: ICI 153110 security is better. Care should be taken to avoid inhalation, swallowing or contact with skin and eyes. If contact occurs, wash with water immediately and seek medical help. During storage and handling, it should be separated from flammable materials and oxidizing agents, and kept sealed.
Last Update：2024-04-09 20:52:54
