874817-14-8 - Names and Identifiers
874817-14-8 - Physico-chemical Properties
Molecular Formula | C19H19NO5
|
Molar Mass | 341.36 |
Density | 1.285±0.06 g/cm3(Predicted) |
Melting Point | 129-130 °C(Solv: ethyl acetate (141-78-6); hexane (110-54-3)) |
Boling Point | 579.4±45.0 °C(Predicted) |
pKa | 10.07±0.46(Predicted) |
874817-14-8 - Introduction
Nature:
1. molecular formula: C21H19NO5
2. molecular weight: 369.38g/mol
3. Appearance: white crystalline solid
4. Melting point: 125-128°C
5. Solubility: Soluble in common organic solvents such as dimethyl sulfoxide and dimethyl formamide
use: D-Serine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, methyl ester is a protective group used in solid phase synthesis and peptide synthesis, and is commonly used in the synthesis of peptide compounds with natural amino acid sequences. It can be removed by a deprotection reaction to facilitate subsequent peptide chain extension.
preparation method: D-Serine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, methyl ester can be prepared by reacting D-serine with Fmoc-Cl (9H-fluoren-9-formyl chloride) under alkaline conditions. Detailed synthetic methods can be found in the relevant scientific literature.
safety information: when using D-Serine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, methyl ester should pay attention to the following safety matters:
1. the compound may be irritating to the eyes, skin and respiratory system, please avoid direct contact.
2. Wear appropriate personal protective equipment such as lab gloves, goggles and protective clothing when operating.
3. When using or handling, please make sure to operate in a well-ventilated laboratory environment to avoid inhaling gas or solution.
4. If you accidentally breathe or come into contact with the compound, please seek the help of a medical professional immediately and go with the safety data sheet of the compound.
Last Update:2024-04-10 22:29:15